嗅球体积与Keros型嗅窝之间是否存在关联？

Is there an association between olfactory bulb volume and the Keros type of fossa olfactoria?

作者信息

Saglam Muzaffer, Salihoglu Murat, Tekeli Hakan, Altundag Aytug, Sivrioglu Ali Kemal, Cayonu Melih

机构信息

From the Departments of *Radiology, †Otorhinolaryngology, ‡Neurology, GATA Haydarpasa Teaching Hospital; §Department of Otorhinolaryngology, Istanbul Surgery Hospital, Istanbul; ∥Department of Radiology, Aksaz Military Hospital, Mugla; and ¶Department of Otorhinolaryngology, Amasya University Training and Research Hospital, Amasya, Turkey.

出版信息

J Craniofac Surg. 2014 Jul;25(4):1273-6. doi: 10.1097/SCS.0000000000000579.

DOI:10.1097/SCS.0000000000000579

PMID:24902111

Abstract

PURPOSE

The purpose of this study was to investigate the relationship between the volume of the olfactory bulb (OB), the depth of the olfactory sulcus (OS), the depth of the fossa olfactoria (FO), and the height of the OB.

METHODS

A total of 54 patients participated (9 women and 45 men; mean [SD] age, 27 [38] y; range, 20-45 y). Magnetic resonance imaging was performed with a 1.5-T system (slice thickness, 1 mm). Measurements of the right and left OB volumes were performed through manual segmentation of the coronal slices. We measured the depth of the FO on the basis of Keros classification on coronal magnetic resonance images. The depth of the OS was measured on the coronal plane at the posterior tangent through the orbital globes. The height of the OB was measured on the coronal plane of the cribriform plate at the highest portion of the OB.

RESULTS

The mean (SD) right OB volume was measured to be 52.21 (13.73) mm3 with a range between 33.90 and 95.70 mm3. The mean (SD) left OB volume was measured to be 53.98 (13.31) mm3 with a range between 31.20 and 94.10 mm3. Type 1, type 2, and type 3 Keros ratios of the FO bilaterally were 12.9% (7/54), 68.5% (37/54), and 3.7% (2/54), respectively. There was no significant relationship between the OB volume and ipsilateral Keros type of FO (right side: P = 0.208; left side: P = 0.164). Similarly, there was no significant relationship between the OB volume and depth of OS on both sides (right side: P = 0.073; left side: P = 0.065). There was no significant association between the Keros type of the right FO and depth of the OS (right side: P = 0.812; left side P = 0.863).

CONCLUSIONS

We conclude that there is no statistical correlation between the OB volume and depth of the FO (Keros type). From the current study, it may be concluded that the depth of the FO may develop largely independent from OB volumes. The individuals without smell disorder have a wide range in OB volume. The method of OB volume measurement that we described is a valid measure of real OB volumes with high reproducibility.

摘要

目的

本研究旨在探讨嗅球（OB）体积、嗅沟（OS）深度、嗅窝（FO）深度与OB高度之间的关系。

方法

共有54例患者参与研究（9名女性和45名男性；平均[标准差]年龄，27[38]岁；范围，20 - 45岁）。使用1.5-T系统进行磁共振成像（层厚，1毫米）。通过对冠状位切片进行手动分割来测量左右OB体积。我们根据冠状位磁共振图像上的Keros分类来测量FO的深度。在通过眼球的后切线的冠状面上测量OS的深度。在筛板的冠状面上OB最高处测量OB的高度。

结果

测得右侧OB平均（标准差）体积为52.21（13.73）立方毫米，范围在33.90至95.70立方毫米之间。测得左侧OB平均（标准差）体积为53.98（13.31）立方毫米，范围在31.20至94.10立方毫米之间。双侧FO的1型、2型和3型Keros比率分别为12.9%（7/54）、68.5%（37/54）和3.7%（2/54）。OB体积与同侧FO的Keros类型之间无显著关系（右侧：P = 0.208；左侧：P = 0.164）。同样，两侧OB体积与OS深度之间也无显著关系（右侧：P = 0.073；左侧：P = 0.065）。右侧FO的Keros类型与OS深度之间无显著关联（右侧：P = 0.812；左侧P = 0.863）。