Carbonero M J, Pascual A, Martínez-Martínez L, Perea E J
Enferm Infecc Microbiol Clin. 1989 Nov;7(9):466-70.
We have comparatively studied the adherence of Staphylococcus epidermidis and S. saprophyticus to epithelial cells of a continuous cellular line of urinary origin (MDCK). The adherence of S. saprophyticus was significantly higher than that of S. epidermidis and this phenomenon was not related to the bacterial surface hydrophobicity or the ability of producing slime in vitro. The pre-incubation of the bacteria with sub-inhibitory concentrations of vancomycin, teicoplanin, amikacin, clindamycin, and roxitromycin did not modify the adherence ability of the microorganisms. Of the antimicrobial agents evaluated, only clindamycin significantly agents evaluated, only clindamycin, significantly inhibited the ability of producing slime of S. saprophyticus strains.
我们比较研究了表皮葡萄球菌和腐生葡萄球菌对源自泌尿系统的连续细胞系（MDCK）上皮细胞的黏附情况。腐生葡萄球菌的黏附能力明显高于表皮葡萄球菌，且这种现象与细菌表面疏水性或体外产黏液能力无关。用亚抑菌浓度的万古霉素、替考拉宁、阿米卡星、克林霉素和罗红霉素对细菌进行预孵育，并未改变微生物的黏附能力。在所评估的抗菌药物中，只有克林霉素显著抑制了腐生葡萄球菌菌株的产黏液能力。
