Department of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Cell. 2014 Jun 5;157(6):1488-1488.e1. doi: 10.1016/j.cell.2014.05.026.
Resident memory T cells (TRM) comprise a subset of nonrecirculating memory T cells that remain positioned at common portals of reinfection. These include barrier tissues such as the mucosae and skin. TRM orchestrate the initial response to pathogens re-encountered at these locales, thereby accelerating protective immune responses.
驻留记忆 T 细胞(TRM)是循环记忆 T 细胞的一个亚群,它们位于再次感染的常见门户处。这些门户包括屏障组织,如黏膜和皮肤。TRM 协调对在这些部位重新遇到的病原体的初始反应,从而加速保护性免疫反应。