Heinrich Jessica, Spießhöfer Jens, Bitter Thomas, Horstkotte Dieter, Oldenburg Olaf
Department of Cardiology, Heart and Diabetes Centre North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany.
Sleep Breath. 2015 May;19(2):489-94. doi: 10.1007/s11325-014-1014-9. Epub 2014 Jun 7.
This study investigated the implications of the revised scoring rules of the American Academy of Sleep Medicine (AASM) in patients with heart failure (HF) with Cheyne-Stokes respiration (CSR).
Ninety-one patients (NYHA ≥II, LVEF ≤45 %; age 73.6 ± 11.3 years old; 81 male subjects) with documented CSR underwent 8 h of cardiorespiratory polygraphy recordings. Those were analyzed by a single scorer strictly applying the 2007 recommended, 2007 alternative, and the 2012 scoring rules.
Compared with the AASM 2007 recommended rules, apnea-hypopnea index (AHI) and hypopnea index (HI) increased significantly when the 2007 alternative and 2012 rules were applied (AHI 34.1 ± 13.5/h vs 37.6 ± 13.2/h vs 38.3 ± 13.2/h, respectively; HI 10.2 ± 9.4/h vs 13.7 ± 10.7/h vs 14.4 ± 11.0/h, respectively; all p < 0.001). Duration of CSR increased significantly with the alternate versus recommended 2007 rules (182.2 ± 117.0 vs 170.1 ± 115.0 min; p ≤ 0.001); there was a significant decrease in CSR duration for the 2012 versus 2007 alternative rules (182.2 ± 117.0 vs 166.7 ± 115.4 min; p ≤ 0.001).
AHI was higher using the AASM 2012 scoring rules due to a less strict definition of hypopnea. Data on the prognostic effects of CSR in patients with HF and the benefits of treatment are mostly based on the AASM 2007 recommended rules, so differences between these and the newer version need to be taken into account.
本研究调查了美国睡眠医学会(AASM)修订的评分规则对伴有陈-施呼吸(CSR)的心力衰竭(HF)患者的影响。
91例记录有CSR的患者(纽约心脏协会心功能分级≥II级,左心室射血分数≤45%;年龄73.6±11.3岁;男性81例)接受了8小时的心肺多导睡眠图记录。由一名评分员严格按照2007年推荐规则、2007年替代规则和2012年评分规则对记录进行分析。
与AASM 2007年推荐规则相比,应用2007年替代规则和2012年规则时,呼吸暂停低通气指数(AHI)和低通气指数(HI)显著增加(AHI分别为34.1±13.5次/小时、37.6±13.2次/小时和38.3±13.2次/小时;HI分别为10.2±9.4次/小时、13.7±10.7次/小时和14.4±11.0次/小时;所有p<0.001)。与2007年推荐规则相比,应用2007年替代规则时CSR持续时间显著增加(182.2±117.0分钟对170.1±115.0分钟;p≤0.001);与2007年替代规则相比,2012年规则的CSR持续时间显著缩短(182.2±117.0分钟对166.7±115.4分钟;p≤0.001)。
由于对低通气的定义不太严格,使用AASM 2012年评分规则时AHI更高。关于CSR对HF患者的预后影响和治疗益处的数据大多基于AASM 2007年推荐规则,因此需要考虑这些规则与新版本之间的差异。