Department of Neonatology, Royal Infirmary of Edinburgh, United Kingdom; and.
Department of Neonatology, University of Edinburgh, United Kingdom.
Pediatrics. 2014 Jul;134(1):e261-5. doi: 10.1542/peds.2013-2053. Epub 2014 Jun 9.
Therapeutic hypothermia is an established standard of care in the treatment of hypoxic-ischemic encephalopathy. Application of therapeutic hypothermia in the clinical setting may reveal a wider spectrum of adverse events than previously reported. We report 5 cases of transient respiratory stridor in 51 infants, occurring at different time points in the cooling process, which appeared to be unrelated to the intubation procedure. Therapeutic hypothermia was associated with transient stridor in this case series. Formal laryngoscopy is required to determine the underlying pathologic etiology.
治疗性低温是治疗缺氧缺血性脑病的既定标准。在临床环境中应用治疗性低温可能会揭示比以前报告的更广泛的不良事件谱。我们报告了 51 例婴儿中 5 例短暂性呼吸喘鸣的病例，这些病例发生在冷却过程中的不同时间点，似乎与插管程序无关。在本病例系列中，治疗性低温与短暂性喘鸣有关。需要进行正式的喉镜检查以确定潜在的病理病因。
