电场引导下胶原蛋白构建块的自组装。
Self-assembly of collagen building blocks guided by electric fields.
作者信息
de la Rica Roberto, Mendoza Ernest, Chow Lesley W, Cloyd Kristy L, Bertazzo Sergio, Watkins Hannah C, Steele Joseph A M, Stevens Molly M
机构信息
Department of Materials, Imperial College London, SW7 2AZ, UK; Department of Bioengineering, Imperial College London, SW7 2AZ, UK; Institute for Biomedical Engineering, Imperial College London, SW7 2AZ, UK.
出版信息
Small. 2014 Oct 15;10(19):3876-9. doi: 10.1002/smll.201400424. Epub 2014 Jun 10.
Abstract
Show me the way: protein building blocks are programmed to assemble hierarchically and yield a defined fiber morphology of micrometric length and precise nanometric diameter. The key step of this method is to align the building blocks with an AC field prior to assembly. The resulting protein nanofibers are straightforwardly integrated with the circuitry for potential applications in bionanotechnology.
摘要
展示方法
蛋白质构建块被编程为分层组装，并产生具有微米级长度和精确纳米级直径的特定纤维形态。该方法的关键步骤是在组装之前用交流电场使构建块对齐。所得的蛋白质纳米纤维可直接与电路集成，用于生物纳米技术的潜在应用。
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