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Biomimetic self-templating supramolecular structures.仿生自模板超分子结构。
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Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofibre and hydrogel.三螺旋至纳米纤维和水凝胶的胶原模拟肽的多层次自组装。
Nat Chem. 2011 Aug 28;3(10):821-8. doi: 10.1038/nchem.1123.
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In situ AFM study of amelogenin assembly and disassembly dynamics on charged surfaces provides insights on matrix protein self-assembly.在带电表面上对釉原蛋白组装和拆卸动态的原位原子力显微镜研究为基质蛋白自组装提供了深入了解。
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Modular design in natural and biomimetic soft materials.自然和仿生软材料中的模块化设计。
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High-yield self-limiting single-nanowire assembly with dielectrophoresis.基于介电泳效应的高产自限性单纳米线组装。
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电场引导下胶原蛋白构建块的自组装。

Self-assembly of collagen building blocks guided by electric fields.

作者信息

de la Rica Roberto, Mendoza Ernest, Chow Lesley W, Cloyd Kristy L, Bertazzo Sergio, Watkins Hannah C, Steele Joseph A M, Stevens Molly M

机构信息

Department of Materials, Imperial College London, SW7 2AZ, UK; Department of Bioengineering, Imperial College London, SW7 2AZ, UK; Institute for Biomedical Engineering, Imperial College London, SW7 2AZ, UK.

出版信息

Small. 2014 Oct 15;10(19):3876-9. doi: 10.1002/smll.201400424. Epub 2014 Jun 10.

DOI:10.1002/smll.201400424
PMID:24913982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5412948/
Abstract

Show me the way: protein building blocks are programmed to assemble hierarchically and yield a defined fiber morphology of micrometric length and precise nanometric diameter. The key step of this method is to align the building blocks with an AC field prior to assembly. The resulting protein nanofibers are straightforwardly integrated with the circuitry for potential applications in bionanotechnology.

摘要

展示方法

蛋白质构建块被编程为分层组装，并产生具有微米级长度和精确纳米级直径的特定纤维形态。该方法的关键步骤是在组装之前用交流电场使构建块对齐。所得的蛋白质纳米纤维可直接与电路集成，用于生物纳米技术的潜在应用。