Domljan Z, Sacer D
Reumatizam. 1989;36(1-6):31-4.
In 65 patients with definite or classical rheumatoid arthritis (RA), according to ARA criteria, and the active disease, we studied the correlation of the clinical status (the number of the swollen and tender joints) with the following laboratory parameters: sedimentation rate, C-reactive protein, serum iron level, haemoglobin content and the number of erythrocytes, leucocytes and thrombocytes in the peripheral blood. All patients received nonsteroidal antiinflammatory drugs; 25,5% of them were on small daily doses of corticosteroids, and most of them (76,5%) were receiving some of the second-line drugs. The acceleration of the sedimentation rate was the most useful laboratory parameter and was found in 96,9% of the patients, followed by an increased quantity of the alpha-2 globulin, sideropenia and a decreased level of haemoglobin. Increase in the CRP titer was found in this study to be of a rather modest value and was increased in only 40% of the RA patients.
在65例根据美国风湿病学会（ARA）标准确诊为明确或典型类风湿关节炎（RA）且处于疾病活动期的患者中，我们研究了临床状况（肿胀和压痛关节的数量）与以下实验室参数之间的相关性：血沉、C反应蛋白、血清铁水平、血红蛋白含量以及外周血中红细胞、白细胞和血小板的数量。所有患者均接受非甾体类抗炎药治疗；其中25.5%的患者每日服用小剂量皮质类固醇，大多数患者（76.5%）正在接受某些二线药物治疗。血沉加快是最有用的实验室参数，在96.9%的患者中出现，其次是α-2球蛋白量增加、缺铁和血红蛋白水平降低。在本研究中发现，CRP滴度升高的价值相当有限，仅在40%的RA患者中升高。
