International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh; Stanford University, Stanford, California; University at Buffalo, Buffalo, New York; Centers for Disease Control and Prevention, Atlanta, Georgia
International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh; Stanford University, Stanford, California; University at Buffalo, Buffalo, New York; Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Trop Med Hyg. 2014 Aug;91(2):415-23. doi: 10.4269/ajtmh.13-0475. Epub 2014 Jun 9.
We conducted a randomized, non-inferiority field trial in urban Dhaka, Bangladesh among mothers to compare microbial efficacy of soapy water (30 g powdered detergent in 1.5 L water) with bar soap and water alone. Fieldworkers collected hand rinse samples before and after the following washing regimens: scrubbing with soapy water for 15 and 30 seconds; scrubbing with bar soap for 15 and 30 seconds; and scrubbing with water alone for 15 seconds. Soapy water and bar soap removed thermotolerant coliforms similarly after washing for 15 seconds (mean log10 reduction = 0.7 colony-forming units [CFU], P < 0.001 for soapy water; mean log10 reduction = 0.6 CFU, P = 0.001 for bar soap). Increasing scrubbing time to 30 seconds did not improve removal (P > 0.05). Scrubbing hands with water alone also reduced thermotolerant coliforms (mean log10 reduction = 0.3 CFU, P = 0.046) but was less efficacious than scrubbing hands with soapy water. Soapy water is an inexpensive and microbiologically effective cleansing agent to improve handwashing among households with vulnerable children.
我们在孟加拉国达卡市进行了一项随机、非劣效性现场试验，比较了母亲使用肥皂水溶液（1.5 升水中加入 30 克粉状清洁剂）与单独使用肥皂和水对手部微生物效果的影响。工作人员在以下洗涤方案前后采集手部冲洗样本：用肥皂水溶液擦洗 15 秒和 30 秒；用肥皂擦洗 15 秒和 30 秒；以及只用清水冲洗 15 秒。用肥皂水溶液和肥皂在 15 秒的洗涤时间后，去除耐热大肠菌群的效果相似（肥皂水溶液的平均对数减少 0.7 个菌落形成单位 [CFU]，P<0.001；肥皂的平均对数减少 0.6 CFU，P=0.001）。将擦洗时间延长至 30 秒并没有提高去除效果（P>0.05）。单独用水擦洗手部也能减少耐热大肠菌群（平均对数减少 0.3 CFU，P=0.046），但效果不如用肥皂水溶液。肥皂水溶液是一种廉价且具有微生物学效果的清洁剂，可改善有脆弱儿童的家庭的洗手效果。
