Oluoch Tom, Katana Abraham, Ssempijja Victor, Kwaro Daniel, Langat Patrick, Kimanga Davies, Okeyo Nicky, Abu-Hanna Ameen, de Keizer Nicolette
Division of Global HIV/AIDS, US Centers for Disease Control and Prevention, Nairobi, Kenya.
Kenya Medical Research Institute, CDC Collaborative Program, Kisumu, Kenya.
J Am Med Inform Assoc. 2014 Nov-Dec;21(6):1009-14. doi: 10.1136/amiajnl-2013-002447. Epub 2014 Jun 9.
There is little evidence that electronic medical record (EMR) use is associated with better compliance with clinical guidelines on initiation of antiretroviral therapy (ART) among ART-eligible HIV patients. We assessed the effect of transitioning from paper-based to an EMR-based system on appropriate placement on ART among eligible patients.
We conducted a retrospective, pre-post EMR study among patients enrolled in HIV care and eligible for ART at 17 rural Kenyan clinics and compared the: (1) proportion of patients eligible for ART based on CD4 count or WHO staging who initiate therapy; (2) time from eligibility for ART to ART initiation; (3) time from ART initiation to first CD4 test.
7298 patients were eligible for ART; 54.8% (n=3998) were enrolled in HIV care using a paper-based system while 45.2% (n=3300) were enrolled after the implementation of the EMR. EMR was independently associated with a 22% increase in the odds of initiating ART among eligible patients (adjusted OR (aOR) 1.22, 95% CI 1.12 to 1.33). The proportion of ART-eligible patients not receiving ART was 20.3% and 15.1% for paper and EMR, respectively (χ(2)=33.5, p<0.01). Median time from ART eligibility to ART initiation was 29.1 days (IQR: 14.1-62.1) for paper compared to 27 days (IQR: 12.9-50.1) for EMR.
EMRs can improve quality of HIV care through appropriate placement of ART-eligible patients on treatment in resource limited settings. However, other non-EMR factors influence timely initiation of ART.
几乎没有证据表明,在符合抗逆转录病毒治疗(ART)条件的HIV患者中,使用电子病历(EMR)与更好地遵循ART起始临床指南相关。我们评估了从纸质病历系统过渡到基于EMR的系统对符合条件患者接受ART合理安排的影响。
我们在肯尼亚17家农村诊所接受HIV治疗且符合ART条件的患者中开展了一项回顾性的、EMR前后对照研究,并比较了:(1)根据CD4计数或世界卫生组织分期符合ART条件并开始治疗的患者比例;(2)从符合ART条件到开始ART的时间;(3)从开始ART到首次CD4检测的时间。
7298例患者符合ART条件;其中54.8%(n = 3998)使用纸质病历系统接受HIV治疗,45.2%(n = 3300)在EMR实施后接受治疗。EMR与符合条件患者开始ART的几率独立增加22%相关(调整后比值比(aOR)为1.22,95%置信区间为1.12至1.33)。对于纸质病历和EMR,未接受ART的符合ART条件患者比例分别为20.3%和15.1%(χ² = 33.5,p < 0.01)。从符合ART条件到开始ART的中位时间,纸质病历为29.1天(四分位间距:14.1 - 62.1),而EMR为27天(四分位间距:12.9 - 50.1)。
在资源有限的环境中,EMR可通过合理安排符合ART条件的患者接受治疗来提高HIV治疗质量。然而,其他非EMR因素也会影响ART的及时起始。