McAtee Jesse R, Martin Sara E S, Cinderella Andrew P, Reid William B, Johnson Keywan A, Watson Donald A
Department of Chemistry and Biochemistry, University of Delaware, Newark, DE, 19716.
Tetrahedron. 2014 Jul 8;70(27-28):4250-4256. doi: 10.1016/j.tet.2014.03.021.
For the first time, nickel-catalyzed silyl-Heck reactions are reported. Using simple phosphine-supported nickel catalysts, direct activation of silyl triflates has been achieved. These results contrast earlier palladium-catalyzed systems, which require iodide additives to activate silyl-triflates. These nickel-based catalysts exhibit good functional group tolerance in the preparation of vinyl silanes, and unlike earlier systems, allows for the incorporation of trialkylsilanes larger than MeSi.
首次报道了镍催化的硅基-Heck反应。使用简单的膦负载镍催化剂，实现了三氟甲磺酸硅酯的直接活化。这些结果与早期的钯催化体系形成对比，后者需要碘化物添加剂来活化三氟甲磺酸硅酯。这些镍基催化剂在乙烯基硅烷的制备中表现出良好的官能团耐受性，并且与早期体系不同，允许引入大于甲基硅的三烷基硅烷。
