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用于硅基 Heck 反应的稳定单组分预催化剂。

A Bench-Stable, Single-Component Precatalyst for Silyl-Heck Reactions.

机构信息

Department of Chemistry and Biochemistry, University of Delaware , Newark, Delaware 19716, United States.

出版信息

Org Lett. 2017 Oct 20;19(20):5641-5644. doi: 10.1021/acs.orglett.7b02807. Epub 2017 Sep 29.

DOI:10.1021/acs.orglett.7b02807
PMID:28960083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5983356/
Abstract

Studies of the silyl-Heck reaction aimed at identifying active palladium complexes have revealed a new species that is formed in situ. This complex has been identified as the palladium iodide dimer, [(JessePhos)PdI], which has been found to be a competent single-component precatalyst for the silyl-Heck reaction. This complex is easily prepared and is temperature, moisture, and air stable. Additionally, this precatalyst provides higher activity and greater reproducibility compared to previous systems.

摘要

旨在确定活性钯配合物的硅基 Heck 反应研究揭示了一种原位形成的新物种。该配合物已被鉴定为二碘化钯（[(JessePhos)PdI]），它被发现是硅基 Heck 反应的一种有能力的单组分前催化剂。该配合物易于制备，并且对温度、湿度和空气稳定。此外，与以前的体系相比，该前催化剂提供了更高的活性和更好的重现性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/504049b8ea7d/nihms968000f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/6a910360f2ed/nihms968000f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/bc8bc39e2f98/nihms968000f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/b761b5880cde/nihms968000f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/3c130e61da3f/nihms968000f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/f4d2e91feea6/nihms968000f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/504049b8ea7d/nihms968000f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/6a910360f2ed/nihms968000f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/97a6cd0c053c/nihms968000f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/bc8bc39e2f98/nihms968000f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/b761b5880cde/nihms968000f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/3c130e61da3f/nihms968000f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/f4d2e91feea6/nihms968000f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/5983356/504049b8ea7d/nihms968000f7.jpg

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