Kim Young-Sung, Ko Youngkyung, Kye Seung-Beom, Yang Seung-Min
Int J Oral Maxillofac Implants. 2014 Jul-Aug;29(4):969-75. doi: 10.11607/jomi.3704. Epub 2014 Jun 10.
An implant abutment should be soft tissue-compatible and resistant to plaque accumulation, and it is preferable for an implant abutment to have color harmony with the surrounding tissues. This study aimed to compare the in vitro fibroblast cell attachment and proliferation on several abutment materials of different colors.
A total of 240 specimens in 6 experimental groups were used: titanium alloy (SM [smooth machined]; gray), cobalt-chrome-molybdenum alloy (CCM; gray), titanium nitride-coated titanium (TiN; yellow), anodic-oxidized titanium (AO; dark pink), composite resin-coated titanium (R; white), and zirconia (Zr; white). The culture plate surface was employed as a control (C). The surface roughness (Sa), developed interfacial area ratio (Sdr), and water contact angle (WCA) were measured. The human gingival fibroblast (HGF-1) attachment and proliferation at the third and seventh days were observed.
Sa values of all experimental groups were < 0.5 μm. Sdr values were between 5% and 8%, except for the Zr group (0.06%). WCA of all groups was greater than 40 degrees. More HGF-1 cells attached on the surfaces of the SM, TiN, and Zr groups than the C group, and the least number of cells were observed on the CCM group (P < .001). On the third day of proliferation, the C group showed significantly greater proliferation than all experimental groups (P < .001). On the seventh day of proliferation, the TiN, AO, Zr, and C groups exhibited twice the number of cells compared to the rest of the groups (P < .001).
Within the limitations of this study, zirconia abutments would be the best choice in the anterior region. Titanium nitride-coated titanium alloy abutments or anodic-oxidized titanium alloy abutments might also be good choices in areas of esthetic challenge or under high occlusal loads.
种植体基台应与软组织相容并能抵抗菌斑积聚，且与周围组织颜色协调更佳。本研究旨在比较不同颜色的几种基台材料上体外成纤维细胞的附着和增殖情况。
使用6个实验组共240个样本：钛合金（SM[机械加工光滑面]；灰色）、钴铬钼合金（CCM；灰色）、氮化钛涂层钛（TiN；黄色）、阳极氧化钛（AO；深粉色）、复合树脂涂层钛（R；白色）和氧化锆（Zr；白色）。以培养板表面作为对照（C）。测量表面粗糙度（Sa）、显露出的界面面积比（Sdr）和水接触角（WCA）。观察人牙龈成纤维细胞（HGF - 1）在第3天和第7天的附着和增殖情况。
所有实验组的Sa值均<0.5μm。除Zr组（0.06%）外，Sdr值在5%至8%之间。所有组的WCA均大于40度。与C组相比，SM、TiN和Zr组表面附着的HGF - 1细胞更多，而CCM组观察到的细胞数量最少（P<.001）。在增殖第3天，C组的增殖明显高于所有实验组（P<.001）。在增殖第7天，TiN、AO、Zr和C组的细胞数量是其他组的两倍（P<.001）。
在本研究的局限性内，氧化锆基台在前牙区将是最佳选择。氮化钛涂层钛合金基台或阳极氧化钛合金基台在美学要求高或咬合负荷大时也可能是不错的选择。
