Nakano Akira, Endo Masato, Hirayama Nobuo, Akai Takashi, Matsubara Hisahiro
Dept. of Surgery, Kumagaya General Hospital.
Gan To Kagaku Ryoho. 2014 May;41(5):641-3.
A 66-year-old man complaining of epigastralgia was referred to our hospital. We examined the patient and diagnosed advanced gastric cancer (ML, type 3, por, cT3, cN3, cH0, cP0, cM1[LYM], cStage IV). A poor outcome was predicted, so we attempted induction chemotherapy and expected tumor downstaging. We chose S-1/CDDP therapy. S-1 was administered orally for 21 days, followed by CDDP div on day 8. Total gastrectomy and lymph node dissection (D2+No. 12a, No. 13,16) was performed using Roux-en-Y reconstruction. Histological examination of the resected stomach and lymph nodes revealed no residual cancer cells, suggesting complete histological remission (grade 3) according to the Japanese classification of gastric carcinoma. The patient has been in good health without recurrence for 12 months after surgery.
一名66岁主诉上腹部疼痛的男性患者被转诊至我院。我们对该患者进行了检查，诊断为进展期胃癌（ML，3型，Borrmann分型，cT3，cN3，cH0，cP0，cM1[LYM]，cIV期）。预计预后不良，因此我们尝试进行诱导化疗并期望肿瘤降期。我们选择了S-1/顺铂疗法。S-1口服21天，随后在第8天静脉滴注顺铂。采用Roux-en-Y重建术进行了全胃切除术和淋巴结清扫（D2+12a组、13组、16组）。对切除的胃和淋巴结进行组织学检查，未发现残留癌细胞，根据日本胃癌分类法提示达到组织学完全缓解（3级）。患者术后12个月身体健康，无复发。
