Coyle D, Flaherty R A, Kelly B D, Hynes S O, Colesky F, Quinlan M R, Corcoran M O, Rogers E
Department of Urology, University College Hospital Galway, Newcastle, Galway, Ireland.
Curr Urol. 2013 Feb;6(4):216-8. doi: 10.1159/000343543. Epub 2013 Feb 8.
Paratesticular liposarcoma is a very rare cause of scrotal mass. It is thought that they arise from spermatic cord lipomas most commonly. While well differentiated tumors tend to share many histological similarities with dedifferentiated tumors, the latter has a much more aggressive phenotype. We present an unusual case of a 69-year-old male with synchronous prostate adenocarcinoma and unilateral renal cell carcinoma who was found to have a dedifferentiated paratesticular liposarcoma. Treatment was with radical resection, preserving the testis, followed by radiotherapy. Unusually recurrence did not occur until 4 years following initial treatment. This case demonstrates the high propensity of dedifferentiated liposarcoma to recur locally and examines the most frequently employed management strategies.
睾丸旁脂肪肉瘤是阴囊肿块的一种非常罕见的病因。人们认为它们最常见于起源于精索脂肪瘤。虽然高分化肿瘤往往与去分化肿瘤有许多组织学相似之处，但后者具有更具侵袭性的表型。我们报告了一例不寻常的病例，一名69岁男性同时患有前列腺腺癌和单侧肾细胞癌，被发现患有去分化睾丸旁脂肪肉瘤。治疗方法是根治性切除，保留睾丸，随后进行放疗。不同寻常的是，直到初始治疗后4年才出现复发。该病例显示了去分化脂肪肉瘤局部复发的高倾向，并探讨了最常用的管理策略。
