Roehrs Timothy, Gumenyuk Valentina, Drake Christopher, Roth Thomas
Sleep Disorders & Research Center, Henry Ford Hospital, Detroit, MI, USA,
Curr Top Behav Neurosci. 2014;21:277-90. doi: 10.1007/7854_2014_324.
Insomnia is a prevalent sleep disorder that is typically comorbid with medical, psychiatric, and other sleep disorders. Yet, it is a disorder with its own course and morbidity that can persist if untreated. This chapter describes the physiological correlates of insomnia expressed during sleep and during the daytime. Together, the data from nighttime and daytime electrophysiology, event-related brain potential recording, neuroimaging studies, sympathetic nervous system, and HPA axis monitoring all suggest that insomnia is a 24 h disorder of hyperarousal.
失眠是一种常见的睡眠障碍,通常与医学、精神和其他睡眠障碍并存。然而,它是一种有自身病程和发病率的疾病,如果不治疗可能会持续存在。本章描述了失眠在睡眠期间和白天所表现出的生理相关性。综合来看,来自夜间和白天的电生理学、事件相关脑电位记录、神经影像学研究、交感神经系统以及下丘脑-垂体-肾上腺(HPA)轴监测的数据均表明,失眠是一种24小时的过度觉醒障碍。