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重复性轻度创伤性脑损伤的累积效应

Cumulative effects of repetitive mild traumatic brain injury.

作者信息

Bailes Julian E, Dashnaw Matthew L, Petraglia Anthony L, Turner Ryan C

机构信息

Department of Neurosurgery, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Evanston, Ill., USA.

出版信息

Prog Neurol Surg. 2014;28:50-62. doi: 10.1159/000358765. Epub 2014 Jun 6.

DOI:10.1159/000358765
PMID:24923392
Abstract

The majority of traumatic brain injuries (TBI) in the USA are mild in severity. Sports, particularly American football, and military experience are especially associated with repetitive, mild TBI (mTBI). The consequences of repetitive brain injury have garnered increasing scientific and public attention following reports of altered mood and behavior, as well as progressive neurological dysfunction many years after injury. This report provides an up-to-date review of the clinical, pathological, and pathophysiological changes associated with repetitive mTBI, and their potential for cumulative effects in certain individuals.

摘要

在美国,大多数创伤性脑损伤(TBI)的严重程度为轻度。体育运动,尤其是美式橄榄球,以及军事经历与重复性轻度TBI(mTBI)的关联尤为密切。在有报告称受伤多年后情绪和行为改变以及进行性神经功能障碍后,重复性脑损伤的后果已引起越来越多的科学和公众关注。本报告对与重复性mTBI相关的临床、病理和病理生理变化,以及它们在某些个体中产生累积效应的可能性进行了最新综述。

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