Simonsen Anne B, Sommerlund Mette, Deleuran Mette, Mortz Charlotte G, Johansen Jeanne D
Department of Dermatology and Venereology, Aarhus University Hospital, 8000 Aarhus C, Denmark.
Acta Derm Venereol. 2015 Feb;95(2):206-10. doi: 10.2340/00015555-1911.
Children are patch tested in the same manner as adults, but little has been done to establish whether positive or negative findings influence the course of skin symptoms. To uncover the course of skin symptoms and the impact of persistent eczema on life quality in paediatric patients referred for patch testing, a retrospective questionnaire was sent to children and adolescents referred for patch testing during a 9-year period. Persistent eczema at follow-up was strongly associated to atopic dermatitis, but was not explained by gender, age, contact allergy or time span from patch testing to follow-up. Among patients without atopic dermatitis, 23.5% reported to suffer from chronic eczema. Persistent eczema increased the risk of severe impairment of life quality. Our findings indicate a significant risk of childhood eczema becoming chronic and affecting life quality considerably. Patch testing did not affect the course of eczema, highlighting the difficulties of avoidance behaviour.
儿童进行斑贴试验的方式与成人相同，但对于阳性或阴性结果是否会影响皮肤症状的病程，目前所做的研究甚少。为了揭示接受斑贴试验的儿科患者的皮肤症状病程以及持续性湿疹对生活质量的影响，我们向在9年期间接受斑贴试验的儿童和青少年发送了一份回顾性调查问卷。随访时的持续性湿疹与特应性皮炎密切相关，但无法用性别、年龄、接触性过敏或从斑贴试验到随访的时间跨度来解释。在没有特应性皮炎的患者中，23.5%报告患有慢性湿疹。持续性湿疹增加了生活质量严重受损的风险。我们的研究结果表明，儿童湿疹有很大风险会发展为慢性，并对生活质量产生相当大的影响。斑贴试验并未影响湿疹的病程，这凸显了避免接触行为的困难。
