Li Tian, Qi Xiwu, Zeng Qiwei, Xiang Zhonghuai, He Ningjia
State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China.
State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400715, China
Database (Oxford). 2014 Jun 11;2014. doi: 10.1093/database/bau054. Print 2014.
Mulberry is an important cultivated plant that has received the attention of biologists interested in sericulture and plant-insect interaction. Morus notabilis, a wild mulberry species with a minimal chromosome number is an ideal material for whole-genome sequencing and assembly. The genome and transcriptome of M. notabilis were sequenced and analyzed. In this article, a web-based and open-access database, the Morus Genome Database (MorusDB), was developed to enable easy-to-access and data mining. The MorusDB provides an integrated data source and an easy accession of mulberry large-scale genomic sequencing and assembly, predicted genes and functional annotations, expressed sequence tags (ESTs), transposable elements (TEs), Gene Ontology (GO) terms, horizontal gene transfers between mulberry and silkworm and ortholog and paralog groups. Transcriptome sequencing data for M. notabilis root, leaf, bark, winter bud and male flower can also be searched and downloaded. Furthermore, MorusDB provides an analytical workbench with some built-in tools and pipelines, such as BLAST, Search GO, Mulberry GO and Mulberry GBrowse, to facilitate genomic studies and comparative genomics. The MorusDB provides important genomic resources for scientists working with mulberry and other Moraceae species, which include many important fruit crops. Designed as a basic platform and accompanied by the SilkDB, MorusDB strives to be a comprehensive platform for the silkworm-mulberry interaction studies. Database URL: http://morus.swu.edu.cn/morusdb.
桑树是一种重要的栽培植物，受到了对养蚕业和植物 - 昆虫相互作用感兴趣的生物学家的关注。川桑（Morus notabilis）是一种染色体数目最少的野生桑树物种，是全基因组测序和组装的理想材料。对川桑的基因组和转录组进行了测序和分析。在本文中，开发了一个基于网络的开放获取数据库——桑树基因组数据库（MorusDB），以实现易于访问和数据挖掘。MorusDB提供了一个集成数据源，便于获取桑树大规模基因组测序和组装、预测基因和功能注释、表达序列标签（EST）、转座元件（TE）、基因本体（GO）术语、桑树与家蚕之间的水平基因转移以及直系同源和旁系同源基因簇。还可以搜索和下载川桑根、叶、树皮、冬芽和雄花的转录组测序数据。此外，MorusDB提供了一个带有一些内置工具和管道的分析工作台，如BLAST、Search GO、Mulberry GO和Mulberry GBrowse，以促进基因组研究和比较基因组学。MorusDB为研究桑树和其他桑科物种（包括许多重要水果作物）的科学家提供了重要的基因组资源。MorusDB被设计为一个基础平台，并与SilkDB一起，努力成为蚕桑相互作用研究的综合平台。数据库网址：http://morus.swu.edu.cn/morusdb 。
