State Key Laboratory of Silkworm Genome Biology, Southwest University, No. 2, Tiansheng Road, Beibei, Chongqing 400715, China.
College of Computer and Information Science, Southwest University, No. 2, Tiansheng Road, Beibei, Chongqing 400715, China.
Database (Oxford). 2020 Jan 1;2020. doi: 10.1093/database/baaa011.
Mulberry is an important economic crop plant and traditional medicine. It contains a huge array of bioactive metabolites such as flavonoids, amino acids, alkaloids and vitamins. Consequently, mulberry has received increasing attention in recent years. MMHub (version 1.0) is the first open public repository of mass spectra of small chemical compounds (<1000 Da) in mulberry leaves. The database contains 936 electrospray ionization tandem mass spectrometry (ESI-MS2) data and lists the specific distribution of compounds in 91 mulberry resources with two biological duplicates. ESI-MS2 data were obtained under non-standardized and independent experimental conditions. In total, 124 metabolites were identified or tentatively annotated and details of 90 metabolites with associated chemical structures have been deposited in the database. Supporting information such as PubChem compound information, molecular formula and metabolite classification are also provided in the MS2 spectral tag library. The MMHub provides important and comprehensive metabolome data for scientists working with mulberry. This information will be useful for the screening of quality resources and specific metabolites of mulberry. Database URL: https://biodb.swu.edu.cn/mmdb/.
桑是一种重要的经济作物和传统药物。它含有大量的生物活性代谢物，如类黄酮、氨基酸、生物碱和维生素。因此，近年来桑受到了越来越多的关注。MMHub（版本 1.0）是第一个公开的桑树叶片中小化合物（<1000 Da）质谱的公共数据库。该数据库包含 936 个电喷雾串联质谱（ESI-MS2）数据，并列出了 91 种桑资源的化合物的具体分布情况，其中有两个生物学重复。ESI-MS2 数据是在非标准化和独立的实验条件下获得的。总共鉴定或暂定注释了 124 种代谢物，数据库中还详细记录了 90 种具有相关化学结构的代谢物。MS2 谱标签库中还提供了支持信息，如 PubChem 化合物信息、分子式和代谢物分类。MMHub 为研究桑的科学家提供了重要而全面的代谢组学数据。这些信息将有助于筛选桑的优质资源和特定代谢物。数据库网址：https://biodb.swu.edu.cn/mmdb/。
