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一项关于一组伊朗成年人红肉消费与中风风险的病例对照研究。

A case-control study on red meat consumption and risk of stroke among a group of Iranian adults.

作者信息

Saneei Parvane, Saadatnia Mohammad, Shakeri Forough, Beykverdi Masumeh, Keshteli Ammar Hassanzadeh, Esmaillzadeh Ahmad

机构信息

1Food Security Research Center,Department of Community Nutrition,School of Nutrition and Food Science,Isfahan University of Medical Sciences,Isfahan,PO Box 81745-151,Islamic Republic of Iran.

2Isfahan Neuroscience Research Center,Isfahan University of Medical Sciences,Isfahan,Islamic Republic of Iran.

出版信息

Public Health Nutr. 2015 Apr;18(6):1084-90. doi: 10.1017/S1368980014001165. Epub 2014 Jun 13.

Abstract

OBJECTIVE

We aimed to examine the association between red meat consumption and stroke in a group of Iranian adults.

DESIGN

A hospital-based case-control study.

SETTING

The study included stroke patients and hospital-based controls. Usual dietary intakes of participants were assessed by means of a validated 168-item semi-quantitative FFQ. Total red meat consumption was calculated by summing up the consumption of red, processed and visceral meats.

SUBJECTS

One hundred and ninety-five cases were stroke patients hospitalized in the neurology ward and 195 controls were recruited from patients hospitalized in other wards with no history of cerebrovascular diseases or neurological disorders.

RESULTS

Participants with stroke were older, more likely to be male and less likely to be obese. Individuals in the highest tertile of red meat intake were 119 % more likely to have stroke (OR=2·19; 95% CI 1·33, 3·60) compared with those in the lowest tertile. After controlling for age, sex and total energy intake, the association between red meat consumption and stroke was strengthened (OR=2·72; 95% CI 1·53, 4·83). This association remained significant even after further controlling for physical activity and smoking as well as dietary intakes. Additional adjustments for BMI, diabetes, hypertension and hyperlipidaemia did not influence the association significantly (OR=2·51; 95 % CI 1·19, 5·09).

CONCLUSIONS

Consumption of red meat was associated with greater odds of having stroke in a group of Iranian adults.

摘要

目的

我们旨在研究一组伊朗成年人中红肉消费与中风之间的关联。

设计

一项基于医院的病例对照研究。

背景

该研究纳入了中风患者和医院对照。通过一份经过验证的包含168个条目的半定量食物频率问卷评估参与者的日常饮食摄入量。红肉总消费量通过将红肉、加工肉和内脏肉的消费量相加得出。

研究对象

195例病例为神经内科病房住院的中风患者,195名对照从其他病房无脑血管疾病或神经疾病病史的住院患者中招募。

结果

中风患者年龄更大,男性比例更高,肥胖可能性更低。与红肉摄入量最低三分位数的个体相比,红肉摄入量最高三分位数的个体患中风的可能性高119%(比值比=2.19;95%置信区间1.33,3.60)。在控制年龄、性别和总能量摄入后,红肉消费与中风之间的关联增强(比值比=2.72;95%置信区间1.53,4.83)。即使在进一步控制身体活动、吸烟以及饮食摄入量后,这种关联仍然显著。对体重指数、糖尿病、高血压和高脂血症进行额外调整并未显著影响这种关联(比值比=2.51;95%置信区间1.19,5.09)。

结论

在一组伊朗成年人中,红肉消费与患中风的几率更高有关。

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