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[中国14岁以上人群支气管哮喘的危险因素]

[Risk factors of bronchial asthma among people aged over 14 years in China].

作者信息

Feng Xiaokai, Lin Jiangtao, Su Nan, Liu Guoliang, Chen Ping, Zhou Xin, Wan Huanying, Yin Kaisheng, Ma Lijun, Wu Changgui, Li Jing, Liu Chuntao, Xie Hua, Tang Wei, Huang Mao, Chen Yan, Liu Yuanhua, Song Liqiang, Chen Xianliang

机构信息

Graduate School of Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

Department of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, China. Email:

出版信息

Zhonghua Yi Xue Za Zhi. 2014 Apr 29;94(16):1209-14.

Abstract

OBJECTIVE

To survey the risk factors of asthma among the people aged over 14 years in China.

METHODS

Home visits for completing epidemiological questionnaires in accordance with stratified cluster random sampling survey were conducted in 8 provinces (cities) of China residents aged over 14 years from February 2010 to August 2011. Asthma was diagnosed based upon case history, clinical signs and lung function test. The SPSS 12.0 software was used for statistic analyses for the epidemiological status of asthma.

RESULTS

Sampling population was composed of 180 099 subjects. Among 164 215 valid questionnaires, there were 79 692 males and 84 523 females, 2 034 had asthma. The overall prevalence rate was 1.2% (2 034/164 215). Correlation analyses showed that the risk factors were smoking (OR = 1.697, 95%CI: 1.547-1.861), breast feeding (OR = 0.801, 95%CI: 0.670-0.959), genetics (OR & 95%CI >1, asthma (OR = 10.440, 95%CI: 8.991-12.112)), complications (OR & 95%CI >1), body mass index (compared with normal weight, overweight (OR = 1.360, 95%CI: 1.212-1.531), obesity (OR = 10.631, 95%CI: 9.570-11.801)) and petting (OR & 95%CI >1).

CONCLUSION

Among Chinese asthmatics aged over 14, their risk factors include host (genetics & obesity) and environmental (smoking, breastfeeding, complications & pets) factors.

摘要

目的

调查我国14岁以上人群哮喘的危险因素。

方法

于2010年2月至2011年8月,按照分层整群随机抽样调查的方法,对我国8个省(市)14岁以上居民进行入户调查以填写流行病学调查问卷。根据病史、临床体征及肺功能检查诊断哮喘。应用SPSS 12.0软件对哮喘的流行病学状况进行统计分析。

结果

抽样人群共180099人。在164215份有效问卷中,男性79692人,女性84523人,哮喘患者2034人。总体患病率为1.2%(2034/164215)。相关性分析显示,危险因素包括吸烟(OR = 1.697,95%CI:1.547 - 1.861)、母乳喂养(OR = 0.801,95%CI:0.670 - 0.959)、遗传因素(OR及95%CI>1)、哮喘家族史(OR = 10.440,95%CI:8.991 - 12.112)、并发症(OR及95%CI>1)、体重指数(与正常体重相比,超重(OR = 1.360,95%CI:1.212 - 1.531),肥胖(OR = 10.631,95%CI:9.570 - 11.801))及饲养宠物(OR及95%CI>1)。

结论

在我国14岁以上哮喘患者中,其危险因素包括宿主因素(遗传因素及肥胖)和环境因素(吸烟、母乳喂养、并发症及宠物)。

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