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[中国14岁以上人群吸烟状况与哮喘流行病学的关系]

[The relationship between smoking status and epidermiology of asthma in people aged over 14 years in China].

作者信息

Nong Y, Lin J T, Chen P, Zhou X, Wan H Y, Yin K S, Ma L J, Wu C G, Li J, Liu C T, Su N, Liu G L, Xie H, Tang W, Huang M, Chen Y H, Liu L J, Song Y, Chen X L, Zhang Y M, Wang W Y, Li W, Sun L C

机构信息

Department of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, Beijing 100029, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2017 Jul 1;56(7):485-489. doi: 10.3760/cma.j.issn.0578-1426.2017.07.003.

DOI:10.3760/cma.j.issn.0578-1426.2017.07.003
PMID:28693055
Abstract

To study the relationship between bronchial asthma and smoking status in Chinese people. Asthma epidemiological survey and stratified-cluster-random method survey were performed in residents over 14 years in 8 provinces (cities) of China from February 2010 to August 2012. Asthma was diagnosed based upon case history, clinical signs and lung function test. Smoking status was investigated by questionnaire. Sampling population was 180 099 and 164 215 were valid. A total of 2 034 subjects were diagnosed as asthma including 79 692 men and 84 523 women. The overall prevalence rate of asthma was 1.24% (2 034/164 215). Smokers were 23.8% (39 137/164 215) in the whole population. Smokers were 34.5% (702/2 034) in asthmatic patients, compared with 23.7% (38 435/162 181) in no-asthmatic population. The incidence of asthma was 1.79% and 1.06% in smokers and non-smokers respectively (<0.001), suggesting that of smoking was 1.70 (95% 1.55-1.86, <0.001). According to asthma control test (ACT) score, the level of asthma control in non smoking group was higher than that in smoking group(43.2% vs 35.3%). The times of hospitalization due to acute exacerbations(0.51 vs 0.41 events/person/year), total hospitalization rate(27.35% vs 20.12%), annual emergency room visits (0.80 vs 0.60 events/person/year) and emergency room visit rate (31.77% vs 24.47%) were all much higher in smoking asthmatic patients than those in non smoking asthmatic patients, indicating that the level of asthma control in smoking patients was significantly worse than in non smoking patients. The smoking rate in Chinese people over 14 years is still high. The prevalence rate of asthma in smokers is significantly higher than that of non-smokers. The level of asthma control in smokers is significantly worse than that in non smokers.

摘要

研究中国人支气管哮喘与吸烟状况之间的关系。于2010年2月至2012年8月在中国8个省(市)对14岁以上居民进行哮喘流行病学调查及分层整群随机抽样调查。根据病史、临床症状及肺功能检查诊断哮喘。通过问卷调查了解吸烟状况。抽样人群为180099人,有效样本为164215人。共有2034名受试者被诊断为哮喘,其中男性79692人,女性84523人。哮喘总体患病率为1.24%(2034/164215)。总体人群中吸烟者占23.8%(39137/164215)。哮喘患者中吸烟者占34.5%(702/2034),非哮喘人群中吸烟者占23.7%(38435/162181)。吸烟者和非吸烟者的哮喘发病率分别为1.79%和1.06%(<0.001),提示吸烟的比值比为1.70(95%可信区间1.55 - 1.86,<0.001)。根据哮喘控制测试(ACT)评分,非吸烟组的哮喘控制水平高于吸烟组(43.2%对35.3%)。吸烟哮喘患者因急性加重的住院次数(0.51次对0.41次/人/年)、总住院率(27.35%对20.12%)、年度急诊就诊次数(0.80次对0.60次/人/年)及急诊就诊率(31.77%对24.47%)均显著高于非吸烟哮喘患者,表明吸烟患者的哮喘控制水平显著差于非吸烟患者。14岁以上中国人的吸烟率仍然很高。吸烟者的哮喘患病率显著高于非吸烟者。吸烟者的哮喘控制水平显著差于非吸烟者。

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