Wallach Daniel, Taïeb Alain
Department of Dermatology, Hôpital Tarnier-Cochin, Paris, France.
Chem Immunol Allergy. 2014;100:81-96. doi: 10.1159/000358606. Epub 2014 May 22.
Atopic dermatitis was described in 1933 but exists since antiquity. We review descriptions of a childhood skin disease compatible with our modern diagnosis of atopic dermatitis, in ancient medicine and in nineteenth century dermatology texts. We identify Hebra's prurigo and Besnier's diathetic prurigo as forerunners of atopic dermatitis, the latter being a synthesis of infantile eczema and prurigo. The pathogenic theories which link atopic dermatitis to humoralistic medicine, to digestive diseases, to allergy may have had consequences on today's reluctance to consider atopic dermatitis as a skin disorder, the treatment of which relies mainly on topicals.
特应性皮炎于1933年被描述，但自古以来就已存在。我们回顾古代医学和19世纪皮肤病学文献中对一种与现代特应性皮炎诊断相符的儿童皮肤病的描述。我们确定黑布拉痒疹和贝西埃素质性痒疹是特应性皮炎的先驱，后者是婴儿湿疹和痒疹的综合。将特应性皮炎与体液医学、消化系统疾病、过敏联系起来的致病理论可能导致了如今人们不愿将特应性皮炎视为一种主要依靠局部用药治疗的皮肤病。
