Gassner Markus
Institute of Allergology and Dermatology and Institute for Family Medicine, University of Zurich, Zurich, Switzerland.
Chem Immunol Allergy. 2014;100:278-86. doi: 10.1159/000359961. Epub 2014 May 22.
Compared with other population groups, the way of life of farmers can be viewed as being similar to that of our ancestors. The settled continuation of generations within certain critical geographical and environmental conditions requires a special local network of knowledge and experience. The immune system provides protection against microbes and their toxins. Each strong reaction impedes an active adaptation. Allergy is therefore a harmful intolerance and represents one of many different paradoxes. The aim of this chapter is to demonstrate some of the interactions of tolerance and adaptation from a historical background.
与其他人群相比，农民的生活方式可以被视为与我们祖先的生活方式相似。在特定的关键地理和环境条件下，世代定居的延续需要一个特殊的本地知识和经验网络。免疫系统提供针对微生物及其毒素的保护。每一次强烈反应都会阻碍积极的适应。因此，过敏是一种有害的不耐受，并且代表了许多不同的悖论之一。本章的目的是从历史背景出发展示一些耐受与适应之间的相互作用。
