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希腊OSD - 6生活质量问卷在接受多导睡眠图检查儿童中的效度验证。

Validation of the Greek OSD-6 quality of life questionnaire in children undergoing polysomnography.

作者信息

Lachanas Vasileios A, Mousailidis George K, Skoulakis Charalampos E, Papandreou Nikolaos, Exarchos Sotirios, Alexopoulos Emmanouel I, Bizakis John G

机构信息

Department of Otorhinolaryngology, University Hospital of Larissa, Greece.

Department of Otorhinolaryngology, University Hospital of Larissa, Greece.

出版信息

Int J Pediatr Otorhinolaryngol. 2014 Aug;78(8):1342-7. doi: 10.1016/j.ijporl.2014.05.024. Epub 2014 Jun 2.

DOI:10.1016/j.ijporl.2014.05.024
PMID:24927640
Abstract

OBJECTIVE

OSD-6 is a disease specific questionnaire for pediatric obstructive sleep apnea (OSA). The aims of this study were to validate OSD-6 in Greek language and correlate OSD-6 with polysomnography results.

STUDY DESIGN

Prospective study.

SETTING

Tertiary referral center.

SUBJECTS AND METHODS

OSD-6 questionnaire was translated to Greek and back to English. A prospective study was conducted on children undergoing overnight polysomnography due to snoring and disrupted sleep. Test-retest evaluation was carried out. Internal consistency and test-retest reliability were evaluated. Validity was assessed by exploring correlations between OSD-6 scores and apnea-hypopnea index (AHI), and by comparing total scores of OSA and non-OSA groups. Responsiveness was assessed by comparing preoperative to postoperative total scores in OSA children who underwent adenotonsillectomy.

RESULTS

Test-retest evaluation of 91 subjects showed good internal consistency (Cronbach's alpha 0.860 for test and 0.873 for retest) and reliability (Pearson's correlation coefficients between test and retest scores: 0.751-0.546; p<0.01). Total and domains' OSD-6 scores and AHI were significantly correlated (Spearman's correlation coefficients: 0.277-0.630; p<0.01), while children with OSA had higher total OSD-6 score than those without OSA (median (interquartile range): 16 (11) vs. 10 (7), respectively; p<0.01), indicating good validity. Postoperative OSD-6 scores were significantly lower than preoperative (2.84 ± 3.21 vs. 15.42 ± 6.48, respectively; p<0.001), suggesting good responsiveness.

CONCLUSION

The Greek version of the OSD-6 questionnaire proved to be a valid instrument with satisfactory internal consistency, reliability, validity and responsiveness. Furthermore, in our study OSD-6 was significantly correlated to polysomnography results.

摘要

目的

OSD - 6是一种针对儿童阻塞性睡眠呼吸暂停(OSA)的疾病特异性问卷。本研究的目的是验证希腊语版的OSD - 6,并将OSD - 6与多导睡眠图结果相关联。

研究设计

前瞻性研究。

研究地点

三级转诊中心。

研究对象与方法

将OSD - 6问卷翻译成希腊语,然后再翻译回英语。对因打鼾和睡眠中断而接受夜间多导睡眠图检查的儿童进行前瞻性研究。进行了重测评估。评估了内部一致性和重测信度。通过探索OSD - 6评分与呼吸暂停低通气指数(AHI)之间的相关性,以及比较OSA组和非OSA组的总分来评估效度。通过比较接受腺样体扁桃体切除术的OSA儿童术前和术后的总分来评估反应性。

结果

对91名受试者的重测评估显示出良好的内部一致性(测试时Cronbach's alpha为0.860,重测时为0.873)和信度(测试分数与重测分数之间的Pearson相关系数:0.751 - 0.546;p<0.01)。OSD - 6的总分及各领域得分与AHI显著相关(Spearman相关系数:0.277 - 0.630;p<0.01),而OSA儿童的OSD - 6总分高于非OSA儿童(中位数(四分位间距):分别为16(11)和10(7);p<0.01),表明效度良好。术后OSD - 6评分显著低于术前(分别为2.84±3.21和15.42±6.48;p<0.001),表明反应性良好。

结论

希腊语版的OSD - 6问卷被证明是一种有效的工具,具有令人满意的内部一致性、信度、效度和反应性。此外,在我们的研究中,OSD - 6与多导睡眠图结果显著相关。

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