胺连接的双杂环和三杂环的合成及抗菌活性
Synthesis and antimicrobial activity of amine linked bis- and tris-heterocycles.
作者信息
Bhanu Prakash T, Dinneswara Reddy G, Padmaja A, Padmavathi V
机构信息
Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India.
Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, Andhra Pradesh, India.
出版信息
Eur J Med Chem. 2014 Jul 23;82:347-54. doi: 10.1016/j.ejmech.2014.06.001. Epub 2014 Jun 3.
PMID:24929288
Abstract
A series of amine linked bis- and tris-heterocycles were prepared from heteroaryl cinnamamides and tested for antimicrobial activity. The compounds 11c and 12c exhibited excellent antibacterial activity while 12a and 12c displayed excellent antifungal activity.
摘要
从杂芳基肉桂酰胺制备了一系列胺连接的双杂环和三杂环化合物，并测试了它们的抗菌活性。化合物11c和12c表现出优异的抗菌活性，而12a和12c表现出优异的抗真菌活性。
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