慢性阻塞性肺疾病急性加重期患者肺康复的结局
Outcome of pulmonary rehabilitation in patients after acute exacerbation of chronic obstructive pulmonary disease.
作者信息
Deepak T H, Mohapatra Prasanta R, Janmeja Ashok K, Sood Parul, Gupta Monica
出版信息
Indian J Chest Dis Allied Sci. 2014 Jan-Mar;56(1):7-12.
BACKGROUND
Pulmonary rehabilitation (PR) is an evidence-based intervention in patients with chronic obstructive pulmonary disease (COPD) which improves the exercise capacity and quality of life (QoL).
METHODS
We studied 60 patients after an episode of acute exacerbation of COPD (AECOPD). They were randomised to receive conventional treatment without pulmonary rehabilitation (CTWPR) (n=30) or, standard treatment plus a 12-week post-exacerbation pulmonary rehabilitation (PEPR) programme in addition. Assessment of exercise capacity by six minute walk test (6MWT) and QoL measured by St George's Respiratory Questionnaire (SGRQ) were carried out initially and at the end of three months.
RESULTS
The baseline characteristics of both the groups were found to be similar. There was a statistically significant increase in the six minute walk distance (6MWD) (increase by 37.9 meters, p< 0.001) and a significant decline in the total SGRQ score (by 3.8 units p< 0.001) in the PEPR group compared to CTWPR group.
CONCLUSION
Early pulmonary rehabilitation in patients with an AECOPD has significant benefits on the QoL and exercise capacity.
背景
肺康复（PR）是一种针对慢性阻塞性肺疾病（COPD）患者的循证干预措施，可提高运动能力和生活质量（QoL）。
方法
我们研究了60例慢性阻塞性肺疾病急性加重期（AECOPD）患者。他们被随机分为两组，一组接受不进行肺康复的常规治疗（CTWPR）（n = 30），另一组接受标准治疗加为期12周的急性加重期后肺康复（PEPR）计划。最初和三个月结束时，通过六分钟步行试验（6MWT）评估运动能力，并通过圣乔治呼吸问卷（SGRQ）测量生活质量。
结果
发现两组的基线特征相似。与CTWPR组相比，PEPR组的六分钟步行距离（6MWD）有统计学意义的增加（增加37.9米，p < 0.001），SGRQ总分有显著下降（下降3.8分，p < 0.001）。
结论
AECOPD患者早期进行肺康复对生活质量和运动能力有显著益处。
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