Herruzo R, Vizcaíno M J, Herruzo I
Department of Preventive Medicine, Public Health and Microbiology, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Department of Preventive Medicine, Public Health and Microbiology, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
J Hosp Infect. 2014 Jul;87(3):175-8. doi: 10.1016/j.jhin.2014.04.006. Epub 2014 May 10.
Microbial contamination of hospital surfaces may be a source of infection for hospitalized patients. We evaluated the efficacy of Glosair™ 400 against two American Type Culture Collection strains and 18 clinical isolates, placed on glass germ-carriers. Carriers were left to air-dry for 60 min and then exposed to a cycle before detection of any surviving micro-organisms. Antibiotic-susceptible Gram-negative bacilli were less susceptible (although not significantly) to this technique than resistant Gram-negative bacilli or Gram-positive cocci and yeasts (3, 3.4 and 4.6 log10 reduction, respectively). In conclusion, in areas that had not been cleaned, aerosolized hydrogen peroxide obtained >3 log10 mean destruction of patients' micro-organisms.
医院环境表面的微生物污染可能是住院患者感染的一个来源。我们评估了Glosair™ 400对放置在玻璃载菌片上的两株美国典型培养物保藏中心菌株和18株临床分离株的杀菌效果。让载菌片自然风干60分钟,然后在检测任何存活微生物之前进行一个循环处理。与耐药革兰氏阴性杆菌或革兰氏阳性球菌及酵母菌相比,对抗生素敏感的革兰氏阴性杆菌对该技术的敏感性较低(尽管差异不显著)(分别减少3、3.4和4.6个对数10)。总之,在未清洁的区域,雾化过氧化氢对患者微生物的平均杀灭率>3个对数10。