Dash Swagatika, Mohanty Swati
CSIR-Institute of Minerals and Materials Technology, Bhubaneswar, India.
Electrophoresis. 2014 Sep;35(18):2656-72. doi: 10.1002/elps.201400084. Epub 2014 Aug 5.
This paper provides an overview on separation of micron and submicron sized biological (cells, yeast, virus, bacteria, etc.) and nonbiological particles (latex, polystyrene, CNTs, metals, etc.) by dielectrophoresis (DEP), which finds wide applications in the field of medical and environmental science. Mathematical models to predict the electric field, flow profile, and concentration profiles of the particles under the influence of DEP force have also been covered in this review. In addition, advancements made primarily in the last decade, in the area of electrode design (shape and arrangement), new materials for electrode (carbon, silicon, polymers), and geometry of the microdevice, for efficient DEP separation of particles have been highlighted.
本文概述了通过介电泳(DEP)分离微米级和亚微米级生物颗粒(细胞、酵母、病毒、细菌等)和非生物颗粒(乳胶、聚苯乙烯、碳纳米管、金属等)的方法,介电泳在医学和环境科学领域有广泛应用。本综述还涵盖了用于预测在DEP力影响下颗粒的电场、流动剖面和浓度剖面的数学模型。此外,还重点介绍了主要在过去十年中在电极设计(形状和排列)、电极新材料(碳、硅、聚合物)以及微器件几何结构方面取得的进展,以实现颗粒的高效DEP分离。