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乳头腺瘤：13例临床病理报告

Adenoma of the nipple: A clinicopathological report of 13 cases.

作者信息

DI Bonito Maurizio, Cantile Monica, Collina Francesca, D'Aiuto Massimiliano, Liguori Giuseppina, DE Cecio Rossella, Botti Gerardo

机构信息

Department of Pathology, National Cancer Institute, Fondazione Pascale Hospital, Naples I-80131, Italy.

Department of Senology, National Cancer Institute, Fondazione Pascale Hospital, Naples I-80131, Italy.

出版信息

Oncol Lett. 2014 Jun;7(6):1839-1842. doi: 10.3892/ol.2014.2000. Epub 2014 Mar 28.

DOI:10.3892/ol.2014.2000
PMID:24932244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4049716/
Abstract

Adenoma of the nipple (AN) represents a rare benign mammary proliferation of lactiferous ducts. It appears as an erosive or ulcerative lesion, which in a number of cases is associated with a serous/hematic secretion. AN may be clinically confused with Paget's disease and histologically with invasive breast carcinoma or breast cancer precursor lesions. Therefore, the histological and immunophenotypic analysis is essential for the differential diagnosis. The present study describes the histopathological characteristics of a first case series of AN.

摘要

乳头腺瘤（AN）是一种罕见的乳腺输乳管良性增生。它表现为一种糜烂性或溃疡性病变，在许多病例中伴有浆液性/血性分泌物。AN在临床上可能与佩吉特病混淆，在组织学上可能与浸润性乳腺癌或乳腺癌前驱病变混淆。因此，组织学和免疫表型分析对于鉴别诊断至关重要。本研究描述了首个乳头腺瘤病例系列的组织病理学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/bfae59086bf0/OL-07-06-1839-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/89e459678036/OL-07-06-1839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/7f17e115804c/OL-07-06-1839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/bfae59086bf0/OL-07-06-1839-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/89e459678036/OL-07-06-1839-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/7f17e115804c/OL-07-06-1839-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f647/4049716/bfae59086bf0/OL-07-06-1839-g02.jpg

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Mammary Paget's Disease Mimicking Benign and Malignant Dermatological Conditions: Clinical Challenges and Diagnostic Considerations.

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2
Immunophenotype of nipple adenoma in a male patient.男性患者乳头腺瘤的免疫表型
Appl Immunohistochem Mol Morphol. 2011 Mar;19(2):190-4. doi: 10.1097/PAI.0b013e3181f1ef0b.
3
Nipple adenoma of breast: a masquerader of malignancy.乳腺乳头腺瘤：一种恶性肿瘤的伪装者。
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Cureus. 2024 Jul 25;16(7):e65378. doi: 10.7759/cureus.65378. eCollection 2024 Jul.
4
Adenoma of the Nipple: A Case Report.乳头腺瘤：一例报告
Cureus. 2024 Jul 8;16(7):e64105. doi: 10.7759/cureus.64105. eCollection 2024 Jul.
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Growth of a Nipple Adenoma After Estrogen Replacement Therapy.雌激素替代疗法后乳头腺瘤的生长
Cureus. 2023 Dec 20;15(12):e50843. doi: 10.7759/cureus.50843. eCollection 2023 Dec.
6
Skin diseases of the nipple and areola complex: A case series study from China.乳头乳晕复合体皮肤病：来自中国的病例系列研究
Front Med (Lausanne). 2023 Mar 28;10:1136482. doi: 10.3389/fmed.2023.1136482. eCollection 2023.
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9
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