School of Chemical Sciences, North Maharashtra University, Jalgaon 425001, Maharashtra, India.
Department of Applied Chemistry, SV National Institute Technology, Surat, Gujrat, India.
Biosens Bioelectron. 2014 Nov 15;61:429-33. doi: 10.1016/j.bios.2014.05.053. Epub 2014 Jun 4.
A new Zn(2+) selective chemosensor (3) was synthesized by condensation of commercially available substituted salicylaldehyde and isonicotinohydrazide, and characterized by single crystal X-ray crystallography. Receptor 3 with Zn(2+) exhibited a highly selective and pronounced enhancement in the fluorescence emission among different cations by forming a 2:1 complex. The receptor can detect Zn(2+) up to nanomolar level (6.75 nM) with good tolerance of other metal ions and can be used for in vitro cellular imaging.
一种新的 Zn(2+)选择性化学传感器（3）通过商业可得的取代水杨醛和异烟酰肼的缩合反应合成，并通过单晶 X 射线晶体学进行了表征。受体 3 与 Zn(2+)形成 2:1 配合物，在不同阳离子中表现出高度选择性和明显增强的荧光发射。该受体可以检测到 Zn(2+)的浓度低至纳摩尔水平（6.75 nM），对其他金属离子具有良好的耐受性，可用于体外细胞成像。
