The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University, Guiyang 550014, China.
School of Basic Medical Science, Guizhou Medical University, Guiyang 550004, China.
Molecules. 2021 Jun 23;26(13):3825. doi: 10.3390/molecules26133825.
A novel turn-on fluorescence probe has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10 mol/L for the quantification of Zn. H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe . An emission titration experiment in the presence of different molar fractions of Zn was used to perform a Job's plot analysis. The results showed that the stoichiometric ratio of the complex formed by and Zn was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand coordinates with one Cu atom in the asymmetric unit. On adding CuCl to the ZnCl/ system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu displaced Zn to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe .
一种新型的荧光探针已被设计出来，它对 Zn 的检测限为 9.53×10 mol/L，具有高选择性和灵敏度。H-NMR 光谱和单晶 X 射线衍射分析表明，席夫碱探针的结构具有非对称性质。在存在不同摩尔分数 Zn 的情况下进行的发射滴定实验用于进行 Job 图分析。结果表明，形成的配合物的化学计量比为 1:1。此外，单核 Cu 配合物的分子结构表明，一个配体与不对称单元中的一个 Cu 原子配位。向 ZnCl/体系中加入 CuCl 后，形成了 Cu-Zn 配合物，并观察到强烈的猝灭行为，这推断出 Cu 取代了 Zn 与探针的亚胺氮原子和羟基氧原子配位。
