旋转式全身电子线照射（RTSEI）技术的机构经验——三十年回顾（1981 - 2012）
Institutional experience with a rotational total skin electron irradiation (RTSEI) technique-A three decade review (1981-2012).
作者信息
Evans Michael D C, Hudon Christine, Podgorsak Ervin B, Freeman Carolyn R
机构信息
Department of Medical Physics, McGill University Health Centre, 1650 Cedar Avenue, Montreal, QC, H3G 1A4 Canada.
Department of Radiation Oncology, McGill University Health Centre, 1650 Cedar Avenue, Montreal, QC, H3G 1A4 Canada.
出版信息
Rep Pract Oncol Radiother. 2013 Jun 17;19(2):120-34. doi: 10.1016/j.rpor.2013.05.002. eCollection 2014 Mar.
Total skin electron irradiation (TSEI) for patients with cutaneous lymphomas is technically challenging, and numerous approaches have been developed to overcome the many field matching problems associated with such a large and complex treatment volume. Since 1981 we have delivered TSEI using a rotational total skin electron irradiation (RTSEI) technique in conjunction with patch, treat and boost fields in order to provide complete skin and dose coverage. Initially we used a 6 MeV electron beam at an extended source-skin distance (SSD) on a modified linear accelerator. More recently we began using a high dose rate electron mode on a commercially available linear accelerator. The RTSEI technique allows the delivery of a seamless surface dose to the majority of the patient's skin surface in a single treatment. In this review paper we present our three-decade experience with the technical development, dosimetry, treatment delivery and clinical outcomes of our RTSEI technique.
对皮肤淋巴瘤患者进行全身皮肤电子线照射（TSEI）在技术上具有挑战性，人们已开发出多种方法来克服与如此大且复杂的治疗体积相关的诸多射野匹配问题。自1981年以来，我们一直采用旋转式全身皮肤电子线照射（RTSEI）技术并结合补量、治疗和增强射野来进行TSEI，以实现完整的皮肤覆盖和剂量覆盖。最初，我们在一台经过改装的直线加速器上，于延长源皮距（SSD）条件下使用6兆电子伏的电子束。最近，我们开始在一台商用直线加速器上使用高剂量率电子模式。RTSEI技术能够在单次治疗中为患者大部分皮肤表面提供无缝的表面剂量。在这篇综述论文中，我们展示了我们在RTSEI技术的技术开发、剂量测定、治疗实施及临床结果方面长达三十年的经验。
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