1 Department of Molecular Microbiology, Institute for Experimental Medicine, Acad. Pavlov Street 12, Saint-Petersburg 197376, Russia.
Biosci Microbiota Food Health. 2013;32(3):81-91. doi: 10.12938/bmfh.32.81. Epub 2013 Jul 25.
The review is devoted to the problems of microbiota and the ways of it correction employing beneficial life bacteria- probiotics. It covers the issues related to the functioning of human microbiota and its importance for the health, individual variability of microbial content, functioning of the probiotics in the human organism and the history of probiotic studies with particular focus on the microbiological investigations in the USSR. The article discusses the safety issues related to probiotics and the problems with probiotic therapy, trying to explain the reasons for the side effects caused by probiotics. The necessity of personified selection of the probiotic strain or individual microbial therapy autoprobiotics is also discussed.
这篇综述致力于研究微生物群及其利用有益生活细菌——益生菌进行纠正的问题。它涵盖了与人类微生物群的功能及其对健康的重要性、微生物含量的个体变异性、益生菌在人体中的作用以及益生菌研究的历史有关的问题,特别关注苏联的微生物学研究。本文讨论了与益生菌相关的安全问题和益生菌治疗的问题,试图解释益生菌引起副作用的原因。还讨论了个体化选择益生菌菌株或个体微生物治疗自益生菌的必要性。