Kymionis George D, Liakopoulos Dimitrios A, Grentzelos Michael A, Diakonis Vasilios F, Klados Nektarios E, Tsoulnaras Konstantinos I, Tsilimbaris Miltiadis K, Pallikaris Ioannis G
*Faculty of Medicine, Vardinoyiannion Eye Institute of Crete (VEIC), University of Crete, Heraklion, Crete, Greece; and †Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL.
Cornea. 2014 Aug;33(8):868-72. doi: 10.1097/ICO.0000000000000169.
The aim of this study was to report 3 cases of persistent epithelial defects (PEDs) successfully treated with the combined topical application of a regenerative agent (RGTA; Cacicol20, OTR3, Paris, France) with a bandage contact lens (BCL).
This is a case series.
Three patients suffering from a PED for 4-8 weeks and unresponsive to conventional therapy were treated with the combined application of an RGTA (Cacicol20) and a silicone hydrogel BCL. The PED healed in all patients after 4-21 days, and no side effects were noted.
The combination of an RGTA (Cacicol20) with a BCL seems to be an effective treatment for PED.
本研究旨在报告3例持续性上皮缺损（PED）患者，通过联合局部应用一种再生剂（RGTA；Cacicol20，OTR3，法国巴黎）和绷带式隐形眼镜（BCL）成功治愈。
这是一个病例系列。
3例患有PED 4 - 8周且对传统治疗无反应的患者，接受了RGTA（Cacicol20）和硅水凝胶BCL的联合应用治疗。所有患者的PED在4 - 21天后愈合，且未观察到副作用。
RGTA（Cacicol20）与BCL联合应用似乎是治疗PED的有效方法。
