由银-氮杂环卡宾配合物催化的醇选择性有氧氧化生成醛、羧酸和亚胺。
Selective aerobic oxidation of alcohols to aldehydes, carboxylic acids, and imines catalyzed by a Ag-NHC complex.
作者信息
Han Lei, Xing Ping, Jiang Biao
机构信息
CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai, 200032, China.
出版信息
Org Lett. 2014 Jul 3;16(13):3428-31. doi: 10.1021/ol501353q. Epub 2014 Jun 17.
Silver NHC catalysts have been developed for the selective oxidation of alcohols to aldehydes or carboxylic acids in the presence of BnMe3NOH or KOH under dry air. The aerobic oxidation conditions are mild, and the yield is excellent. Further tandem catalysis enables the one-pot synthesis of imines in excellent yield. Only 0.1 mol % of the catalyst is required.
银氮杂环卡宾催化剂已被开发用于在干燥空气中，在苄基三甲基氢氧化铵（BnMe3NOH）或氢氧化钾存在下，将醇选择性氧化为醛或羧酸。有氧氧化条件温和，产率优异。进一步的串联催化能够以优异的产率实现亚胺的一锅法合成。仅需0.1摩尔%的催化剂。
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