Department of Energy Science, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Center for Integrated Nanostructure Physics, Institute for Basic Science (IBS), Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Sci Rep. 2017 Jun 9;7(1):3146. doi: 10.1038/s41598-017-03468-4.
A highly efficient and simple chemoselective aerobic oxidation of primary alcohols to either aldehydes or carboxylic acids in the presence of nitric acid was developed, utilising 5 wt% graphene oxide as a carbocatalyst under ambient reaction conditions. Carboxylic acid functional groups on graphene oxides played a vital role in carbocatalyst activity, greatly influencing both the reactivity and selectivity. We also applied this protocol to a variant of the Knoevenagel condensation for primary alcohols and malonates with a secondary amine co-catalyst via cooperative catalysis.
在环境反应条件下，利用 5wt%氧化石墨烯作为碳催化剂，开发出一种高效且简单的伯醇选择性有氧氧化为醛或酸的方法。氧化石墨烯上的羧酸官能团在碳催化剂的活性中起着至关重要的作用，极大地影响了反应性和选择性。我们还通过协同催化，将该方案应用于伯醇和丙二酸酯与仲胺共催化剂的 Knoevenagel 缩合的变体。
