Harris Aaron M, Beekmann Susan E, Polgreen Philip M, Moore Matthew R
Respiratory Disease Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia.
University of Iowa Carver College of Medicine, Iowa City, Iowa.
Diagn Microbiol Infect Dis. 2014 Aug;79(4):454-7. doi: 10.1016/j.diagmicrobio.2014.05.008. Epub 2014 May 17.
Streptococcus pneumoniae (pneumococcus) is the most common bacterial etiology of community-acquired pneumonia (CAP) in adults, a leading cause of death. The majority of pneumococcal CAP is diagnosed by blood culture, which likely underestimates the burden of disease. The 2007 CAP guidelines recommend routine use of the rapid pneumococcal urinary antigen (UAg) test. To assess the how pneumococcal UAg testing is being used among hospitalized adult CAP patients and what barriers restrict its use, a Web-based survey was distributed in 2013 to 1287 infectious disease physician members of the Emerging Infectious disease Network of the Infectious Disease Society of America. Of 493 eligible responses, 65% use the pneumococcal UAg test. The primary barrier to UAg use was availability (46%). UAg users reported ordering fewer other diagnostic tests and tailoring antibiotic therapy. Increased access to UAg tests could improve pneumonia management and pneumococcal CAP surveillance.
肺炎链球菌是成人社区获得性肺炎（CAP）最常见的细菌病因，是主要的死亡原因。大多数肺炎球菌性CAP通过血培养诊断，这可能低估了疾病负担。2007年CAP指南建议常规使用快速肺炎球菌尿抗原（UAg）检测。为评估住院成年CAP患者中肺炎球菌UAg检测的使用情况以及限制其使用的障碍，2013年向美国传染病学会新发传染病网络的1287名传染病科医生会员进行了一项基于网络的调查。在493份合格回复中，65%使用肺炎球菌UAg检测。UAg使用的主要障碍是可获得性（46%）。UAg使用者报告减少了其他诊断检测的开具，并调整了抗生素治疗。增加UAg检测的可及性可改善肺炎管理和肺炎球菌性CAP监测。
