Thompson Ronald G, Shmulewitz Dvora, Meyers Jacquelyn L, Stohl Malki, Aharonovich Efrat, Spivak Baruch, Weizman Abraham, Frisch Amos, Grant Bridget F, Hasin Deborah S
Department of Psychiatry, Columbia University, New York, NY 10032, USA.
Department of Psychiatry, Columbia University, New York, NY 10032, USA; New York State Psychiatric Institute, New York, NY 10032, USA.
Drug Alcohol Depend. 2014 Aug 1;141:85-91. doi: 10.1016/j.drugalcdep.2014.05.009. Epub 2014 May 28.
Parental divorce and psychopathology are well-documented risk factors for alcohol use disorders (AUD) in the United States and other countries where divorce is common and per capita total alcohol consumption is moderate to high. However, little is known about these relationships in countries where divorce and alcohol problems are less common, such as Israel.
Israeli adult household residents (N=797) age 21-45 were interviewed in person between 2007 and 2009. Logistic regression models were used to examine main and additive interaction effects of parental divorce and psychopathology on lifetime DSM-IV AUD, adjusting for age, gender, and ethnicity.
Parental divorce (OR=2.18, p≤0.001) and parental psychopathology (OR=1.61, p≤0.01) were independently associated with lifetime AUD and, when considered together, showed significant interaction (p=0.026). Specifically, the effect of divorce on AUD was only significant among those who also reported parental psychopathology.
This is the first study showing the influence of parental divorce and psychopathology on risk for AUD among Israeli adults, where both divorce and AUD are less common than in the United States. Alcohol prevention and treatment professionals should recognize that children who experience parental divorce and/or psychopathology could be more vulnerable to later developing AUD than those whose parents remain together and without psychopathology.
在美国以及其他离婚普遍且人均酒精总消费量处于中高水平的国家，父母离异和精神病理学是酒精使用障碍（AUD）的充分记录在案的风险因素。然而，在离婚和酒精问题不太常见的国家，如以色列，对于这些关系却知之甚少。
2007年至2009年期间，对年龄在21至45岁之间的797名以色列成年家庭居民进行了面对面访谈。使用逻辑回归模型来检验父母离异和精神病理学对终生DSM-IV酒精使用障碍的主要和累加交互作用，同时对年龄、性别和种族进行了调整。
父母离异（优势比=2.18，p≤0.001）和父母精神病理学（优势比=1.61，p≤0.01）与终生酒精使用障碍独立相关，并且当综合考虑时，显示出显著的交互作用（p=0.026）。具体而言，离婚对酒精使用障碍的影响仅在那些也报告有父母精神病理学问题的人群中显著。
这是第一项显示父母离异和精神病理学对以色列成年人酒精使用障碍风险影响的研究，在以色列，离婚和酒精使用障碍都比美国少见。酒精预防和治疗专业人员应认识到，经历父母离异和/或精神病理学问题的儿童可能比父母未离异且无精神病理学问题的儿童更容易在以后患上酒精使用障碍。
