Tao Yuankai K, Srivastava Sunil K, Ehlers Justis P
Ophthalmic Imaging Center, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Ophthalmic Imaging Center, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Biomed Opt Express. 2014 May 20;5(6):1877-85. doi: 10.1364/BOE.5.001877. eCollection 2014 Jun 1.
We present novel optical and mechanical designs for a microscope-integrated intraoperative optical coherence tomography (iOCT) system with enhanced function and ergonomics for visualization of ophthalmic surgical maneuvers. Integration of an electrically tunable lens allows rapid focal plane adjustment and iOCT imaging of both anterior and posterior segment tissue microstructures while maintaining parfocality with the ophthalmic surgical microscope. We demonstrate novel visualization of instrument positions relative to tissue layers of interest as colormap overlays onto en face OCT data, which may provide integrative display of volumetric information during surgical maneuvers. Finally, we implement a heads-up display system to provide real-time feedback as proof-of-principle for iOCT-guided ophthalmic surgery.
我们展示了一种用于显微镜集成式术中光学相干断层扫描（iOCT）系统的新颖光学和机械设计，该系统具有增强的功能和人体工程学特性，用于可视化眼科手术操作。集成电可调透镜可实现快速焦平面调整，并对前段和后段组织微结构进行iOCT成像，同时保持与眼科手术显微镜的共焦。我们展示了相对于感兴趣组织层的器械位置的新颖可视化，作为彩色地图叠加在正面OCT数据上，这可以在手术操作期间提供体积信息的综合显示。最后，我们实施了一个平视显示系统，以提供实时反馈，作为iOCT引导眼科手术原理验证。
