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自然杀伤细胞活性:早期研究、进展及开创性观察

Natural killer activity: early days, advances, and seminal observations.

作者信息

Ortaldo John R, Wiltrout Robert H, Reynolds Craig W

机构信息

Laboratory of Experimental Immunology, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health.

Offlce of the Director, National Cancer Institute, National Institutes of Health.

出版信息

Crit Rev Oncog. 2014;19(1-2):1-13. doi: 10.1615/critrevoncog.2014011125.

Abstract

This manuscript describes the early history of NK cell discovery, with emphasis on the events in the first decade of NK cell studies, 1972-1982. The authors highlight some of the earliest and most important observations that would later prove to be milestones in the study of NK cells and their activity.

摘要

本手稿描述了自然杀伤细胞发现的早期历史,重点讲述了1972年至1982年自然杀伤细胞研究头十年中的一些事件。作者着重介绍了一些最早且最重要的观察结果,这些结果后来被证明是自然杀伤细胞及其活性研究中的里程碑。

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