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发生于大腿的多形性透明变性血管扩张性肿瘤:一例报告。

Pleomorphic hyalinizing angiectatic tumor arising in the thigh: A case report.

作者信息

Suzuki Kayo, Yasuda Taketoshi, Hori Takeshi, Oya Takeshi, Watanabe Kenta, Kanamori Masahiko, Kimura Tomoatsu

机构信息

Department of Orthopedic Surgery, University of Toyama, Toyama, Toyama 930-0194, Japan.

Department of Orthopedic Surgery, Iiyama Red Hospital, Iiyama, Nagano 89-2233, Japan.

出版信息

Oncol Lett. 2014 Apr;7(4):1249-1252. doi: 10.3892/ol.2014.1883. Epub 2014 Feb 14.

Abstract

Pleomorphic hyalinizing angiectatic tumors (PHATs) are rare non-metastasizing tumors of uncertain lineage. The current study presents a case of PHAT arising in the thigh of a 68-year-old female and examines the clinicopathological characteristics of the tumor. Magnetic resonance imaging (MRI) revealed an intramuscular mass located in the adductor longus. The tumor was surrounded by lipomatous tumor. Wide resectioning was performed for the internal tumor, whereas intralesional resectioning was performed for the external tumor. Histopathologically, the internal lesion was diagnosed as a PHAT and the external lesion was diagnosed as an hemosiderotic fibrolipomatous lesion (HFLL). No recurrence or metastases were identified during the 6-year follow-up period. As the adipose tissue surrounding the PHAT resembled a HFLL, therefore, the association between 'early PHAT' and HFLL is discussed. Although PHATs may represent low-grade sarcomas, HFLLs may be benign tumors.

摘要

多形性透明变性血管扩张性肿瘤(PHATs)是一种罕见的、谱系不明的非转移性肿瘤。本研究报告了一例发生于一名68岁女性大腿的PHAT病例,并对该肿瘤的临床病理特征进行了研究。磁共振成像(MRI)显示长收肌内有一肌内肿块。肿瘤被脂肪瘤样肿瘤包绕。对内部肿瘤进行了广泛切除,而对外部肿瘤进行了瘤内切除。组织病理学检查显示,内部病变诊断为PHAT,外部病变诊断为含铁血黄素性纤维脂肪瘤样病变(HFLL)。在6年的随访期内未发现复发或转移。由于PHAT周围的脂肪组织类似HFLL,因此,讨论了“早期PHAT”与HFLL之间的关联。虽然PHATs可能为低级别肉瘤,但HFLLs可能是良性肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/3961218/f00e2a6fbb68/OL-07-04-1249-g00.jpg

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