Children's Outcomes Research Program, University of Colorado Denver, Aurora, Colorado, United States of America.
Institute for Social Research, University of Michigan, Ann Arbor, Michigan, United States of America.
PLoS One. 2014 Jun 19;9(6):e100193. doi: 10.1371/journal.pone.0100193. eCollection 2014.
Validated measures that can accurate describe young adults' HPV vaccination attitudes and how these relate to vaccination intention and receipt are needed for developing interventions to improve low HPV vaccination levels. The Carolina HPV Immunization Attitudes Scale (CHIAS) is a validated measure of these outcomes that was originally designed for parents.
To assess the performance of the CHIAS among young adult women using an exploratory factor analysis.
A convenience sample of 139 young adult women (age 18-26 years) were given the CHIAS measure at baseline. Factor analysis was used to determine attitudinal factor groupings and the association of these factors with HPV vaccination intention. A 6-month follow up assessment examined the stability of the CHIAS over time and the association of baseline vaccine factors with vaccine receipt.
Five factors loaded on to the CHIAS in young adults - "Barriers," "Harms," "Effectiveness," "Risk Denial" and "Uncertainty," - which was similar to the factor loadings of CHIAS for parents. "Harms" was the factor most consistently associated with vaccination intention at all time points assessed. Only 5 women had received or made an appointment to receive the vaccine at the 6-month follow-up.
In terms of categorizing HPV vaccination attitudes, the CHIAS appears to have similar performance among young adults as in parents. However, additional studies are needed to assess the utility of the CHIAS for predicting HPV vaccine receipt among the young adult population.
需要有效的措施来准确描述年轻人的 HPV 疫苗接种态度,以及这些态度如何与接种意愿和接种情况相关,以便制定干预措施来提高 HPV 疫苗接种率。卡罗莱纳 HPV 免疫态度量表(CHIAS)是一种经过验证的衡量这些结果的工具,最初是为父母设计的。
使用探索性因素分析评估 CHIAS 在年轻成年女性中的表现。
对 139 名年龄在 18-26 岁的年轻成年女性进行了 CHIAS 测量。使用因子分析来确定态度因素分组,以及这些因素与 HPV 疫苗接种意愿的关联。6 个月的随访评估了 CHIAS 在一段时间内的稳定性,以及基线疫苗因素与疫苗接种情况的相关性。
在年轻成年人中,CHIAS 有五个因素负载 - “障碍”、“危害”、“有效性”、“风险否认”和“不确定性”,与父母的 CHIAS 因素负载相似。“危害”是在所有评估时间点与接种意愿最一致相关的因素。只有 5 名女性在 6 个月的随访中接受了疫苗接种或预约了疫苗接种。
在分类 HPV 疫苗接种态度方面,CHIAS 在年轻成年人中的表现与在父母中相似。然而,需要进一步的研究来评估 CHIAS 在预测年轻人群中 HPV 疫苗接种情况方面的效用。