ten Berge Josianne C E M, van Daele Paul L A, Rothova Aniki
a Department of Ophthalmology , Erasmus MC, University Medical Center Rotterdam , Rotterdam , The Netherlands , and.
b Department of Immunology, Erasmus MC , University Medical Center Rotterdam , Rotterdam , The Netherlands.
Ocul Immunol Inflamm. 2016;24(1):113-4. doi: 10.3109/09273948.2014.925126. Epub 2014 Jun 19.
Rubella virus is involved in the pathogenesis of Fuchs heterochromic uveitis and almost all cases in Europe show an active antibody production in the aqueous humor against rubella virus. Herein we report a case of a fully vaccinated patient with common variable immunodeficiency who developed unilateral Fuchs heterochromic uveitis secondary to rubella virus which was proven by intraocular fluid examination. Awareness of rubella associated anterior uveitis should remain also in vaccinated patients, especially those without a fully competent immune system.
风疹病毒与富克斯异色性葡萄膜炎的发病机制有关,欧洲几乎所有病例的房水中都有针对风疹病毒的活跃抗体产生。在此,我们报告一例完全接种疫苗但患有常见可变免疫缺陷的患者,该患者继发于风疹病毒感染而发生单侧富克斯异色性葡萄膜炎,这通过眼内液检查得以证实。对于接种过疫苗的患者,尤其是那些免疫系统不完全健全的患者,也应警惕风疹相关的前葡萄膜炎。