Lasebikan Omolade A, Nwadinigwe Cajetan U, Onyegbule Eramus C
Niger J Med. 2014 Jan-Mar;23(1):46-50.
Primary bone tumour is a challenge to Orthopaedic surgeons working in developing countries due to late presentation as a result of ignorance and poverty. This is further compounded by limited number of specialist personnel, diagnostic and therapeutic centres. Consequently, they are associated with high rate of morbidity and mortality, which can be reduced with early presentation.
This is a retrospective review of all histologically proven primary bone tumours seen at National Orthopaedic hospital Enugu, South east Nigeria, over a 6 year period.
Sixty eight (68) cases met the study criteria and were reviewed. Male:Female ratio was 1.35:1, with a mean age of 22.8 years and peak frequency in the 11-20 years age range. A total of 28 (41.1%) were benign, 21 (30.9%) were malignant while 19 (27.9%) were tumour-like conditions. The commonest benign tumour was osteochondroma, accounting for 44.7% of non-malignant lesions, while fibrous dysplasia was the commonest tumour-like condition (23.4%). Primary malignant bone tumours accounted for 30.9% of all pathologies, with osteosarcoma (17) accounting for 80.1% of all malignant lesions. The commonest region affected is the leg i.e proximal tibia. Duration of symptoms before presentation ranged from 1 month to 12 years, with the commonest presenting complaint being a painless lump.
Primary bone tumours is commonest in young males, usually benign and affecting the Tibia. Associated late presentation results in increased morbidity and mortality. Hence, efforts need to be geared towards public enlightenment in developing countries, to ensure early presentation, thereby reducing morbidity and mortality.
由于无知和贫困导致就诊延迟，原发性骨肿瘤对在发展中国家工作的骨科医生来说是一项挑战。专家人员、诊断和治疗中心数量有限使这一情况更加复杂。因此，它们与高发病率和高死亡率相关，而早期就诊可降低这种情况。
这是一项对尼日利亚东南部埃努古国立骨科医院6年间所有经组织学证实的原发性骨肿瘤病例的回顾性研究。
68例病例符合研究标准并接受了审查。男女比例为1.35:1，平均年龄为22.8岁，发病高峰在11至20岁年龄组。共有28例（41.1%）为良性，21例（30.9%）为恶性，19例（27.9%）为肿瘤样病变。最常见的良性肿瘤是骨软骨瘤，占非恶性病变的44.7%，而纤维发育不良是最常见的肿瘤样病变（23.4%）。原发性恶性骨肿瘤占所有病理类型的30.9%，骨肉瘤（17例）占所有恶性病变的80.1%。最常受累的部位是腿部，即胫骨近端。就诊前症状持续时间从1个月到12年不等，最常见的主诉是无痛性肿块。
原发性骨肿瘤在年轻男性中最常见，通常为良性，且累及胫骨。相关的就诊延迟导致发病率和死亡率增加。因此，发展中国家需要努力开展公众宣传，以确保早期就诊，从而降低发病率和死亡率。
