Agarwal Ritesh
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India,
Mycopathologia. 2014 Dec;178(5-6):447-56. doi: 10.1007/s11046-014-9767-z. Epub 2014 Jun 20.
Allergic bronchopulmonary aspergillosis (ABPA) is an insidious pulmonary disorder caused by hypersensitivity reactions mounted against Aspergillus fumigatus. Usually, complicating the course of patients with asthma and cystic fibrosis, the affliction has recently been described in chronic obstructive pulmonary disease and pulmonary tuberculosis-related fibrocavitary disease. Patients commonly present with poorly controlled asthma, recurrent pulmonary infiltrates and bronchiectasis. More than six decades have elapsed since the first description of this entity; however, the condition remains poorly understood. The International Society for Human and Animal Mycology has formed a working group to address the deficiencies associated with understanding of this disorder. New criteria have been laid down for diagnosis and staging of the disorder, so as to simplify the identification and management of this condition. This review summarizes the recent advances that have taken place in this condition with special emphasis on the burden and distinct character of ABPA in the Indian subcontinent.
变应性支气管肺曲霉病（ABPA）是一种由针对烟曲霉的超敏反应引起的隐匿性肺部疾病。该疾病通常使哮喘和囊性纤维化患者的病程复杂化，最近在慢性阻塞性肺疾病和肺结核相关的纤维空洞性疾病中也有描述。患者通常表现为哮喘控制不佳、反复肺部浸润和支气管扩张。自首次描述该疾病实体以来，已经过去了六十多年；然而，人们对这种疾病仍然知之甚少。国际人类和动物真菌学会已经成立了一个工作组，以解决与理解这种疾病相关的不足。已经制定了该疾病诊断和分期的新标准，以便简化这种疾病的识别和管理。本综述总结了该疾病最近取得的进展，特别强调了ABPA在印度次大陆的负担和独特特征。
