Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Pulmonology, CK Birla Hospitals, Kolkata, India.
Clin Exp Allergy. 2023 Jul;53(7):751-764. doi: 10.1111/cea.14319. Epub 2023 Apr 16.
Allergic bronchopulmonary aspergillosis (ABPA) is a lung disorder caused by immune-mediated reactions mounted against Aspergillus fumigatus. The disorder most commonly complicates the course of patients with asthma and cystic fibrosis. From its first description in 1952, significant advances have been made in understanding the pathogenesis and the diagnosis and treatment of ABPA. In the last two decades, most research on ABPA has been published from India. The prevalence and clinical presentation may differ in India from that reported elsewhere. Herein, we review the epidemiology, clinical and radiological characteristics, and distinctive features of ABPA in the Indian subcontinent. To support the review, we surveyed pulmonologists nationwide to understand the challenges in diagnosing and managing ABPA. The survey has yielded valuable insights into the practices associated with the diagnosis and management of ABPA in India.
变应性支气管肺曲霉病（ABPA）是一种由免疫介导的对抗烟曲霉的反应引起的肺部疾病。该疾病最常使哮喘和囊性纤维化患者的病情复杂化。自 1952 年首次描述以来，人们在理解 ABPA 的发病机制以及诊断和治疗方面取得了重大进展。在过去的二十年中，大多数关于 ABPA 的研究都发表在印度。ABPA 的流行情况和临床表现可能与其他地方报道的不同。本文综述了印度次大陆 ABPA 的流行病学、临床和放射学特征以及独特表现。为了支持综述，我们对全国的肺病学家进行了调查，以了解诊断和管理 ABPA 方面的挑战。该调查深入了解了与印度 ABPA 诊断和管理相关的实践。
