Buraidah Central Hospital, Buraidah, Al-Qaseem, Saudi Arabia.
CMH Kharian, Pakistan.
Int J Surg. 2014;12(8):868-71. doi: 10.1016/j.ijsu.2014.06.005. Epub 2014 Jun 16.
Role of prophylactic antibiotics in Milligan Morgan hemorrhoidectomy - A prospective, randomized control trial.
Randomized control trial.
Combined Military Hospital Malir, Bannu and HIT hospital Taxilla, September 2008 to February 2011.
Patients undergoing Milligan Morgan hemorrhoidectomy for grade III and IV hemorrhoids were randomized in 2 groups by using computer generated table. Group A did not receive any prophylactic antibiotic whereas group B received 500 mg I/V metronidazole and 1 g Ceftriaxone I/V before induction of anesthesia. All the patients had standardized post operative care. Pain scores on 100 mm Visual Analogue Scale and consumption of oral analgesics were noted from 1st to 7th post operative day. Time required for complete healing was also noted. Data was entered on SPSS 16.0 and p value was calculated.
Out of 100 patients, 96 patients (47 in group A and 49 in group B) completed the study. Demographical data was comparable in both the groups. There was no difference in the pain scores, analgesic consumption and rate of healing between both the groups.
Prophylactic antibiotics have got no role in cases of Milligan Morgan hemorrhoidectomy.
预防性抗生素在 Milligan Morgan 痔切除术的作用——一项前瞻性、随机对照试验。
随机对照试验。
2008 年 9 月至 2011 年 2 月，在马拉里三军总医院和 Taxilla 的 HIT 医院进行。
接受 Milligan Morgan 痔切除术治疗 III 级和 IV 级痔疮的患者通过计算机生成的表格随机分为两组。A 组未接受任何预防性抗生素，而 B 组在麻醉诱导前接受 500mg I/V 甲硝唑和 1g I/V 头孢曲松。所有患者均接受标准化术后护理。从术后第 1 天到第 7 天记录视觉模拟评分 100mm 的疼痛评分和口服止痛药的使用情况。还记录了完全愈合所需的时间。数据输入 SPSS 16.0 并计算 p 值。
100 例患者中，96 例（A 组 47 例，B 组 49 例）完成了研究。两组的人口统计学数据无差异。两组之间的疼痛评分、镇痛药使用量和愈合率均无差异。
在 Milligan Morgan 痔切除术的情况下，预防性抗生素没有作用。
