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葡萄膜炎作为多发性硬化症的预后因素。

Uveitis as a prognostic factor in multiple sclerosis.

机构信息

Istanbul Faculty of Medicine, Istanbul University, Turkey.

Istanbul Faculty of Medicine, Istanbul University, Turkey/Institute for Experimental Medicine (DETAE), Istanbul University, Turkey

出版信息

Mult Scler. 2015 Jan;21(1):105-7. doi: 10.1177/1352458514539782. Epub 2014 Jun 16.

DOI:10.1177/1352458514539782
PMID:24948689
Abstract

Uveitis is occasionally encountered in multiple sclerosis (MS) patients. The objective of this report is to investigate whether uveitis has a prognostic impact on the clinical course of MS. Several clinical and demographic features were compared between 41 MS patients with uveitis and 100 randomly selected MS patients without uveitis. While there were no significant differences by means of gender, age of MS onset, oligoclonal band positivity and disease duration, EDSS and progression index (PI) scores of MS patients with uveitis were significantly lower than those without uveitis (p = 0.004 and <0.001, respectively). Our results suggest that uveitis might be used as a good prognostic factor.

摘要

葡萄膜炎偶尔会发生在多发性硬化症(MS)患者中。本报告的目的是探讨葡萄膜炎是否对 MS 的临床病程有预后影响。将 41 例 MS 合并葡萄膜炎患者与 100 例随机选择的 MS 无葡萄膜炎患者进行了比较,比较了他们的若干临床和人口统计学特征。尽管在性别、MS 发病年龄、寡克隆带阳性和疾病持续时间方面没有显著差异,但葡萄膜炎患者的 EDSS 和进展指数(PI)评分明显低于无葡萄膜炎患者(p = 0.004 和 <0.001)。我们的结果表明,葡萄膜炎可能是一个良好的预后因素。

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