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抗菌药物耐药性概述及其对公共卫生的意义。

An overview of antimicrobial resistance and its public health significance.

作者信息

Balsalobre Livia Carminato, Dropa Milena, Matté Maria Helena

机构信息

Laboratório de Saúde Pública Faculdade de Saúde Pública Universidade de São Paulo São PauloSP Brazil.

出版信息

Braz J Microbiol. 2014 Apr 18;45(1):1-5. doi: 10.1590/S1517-83822014005000033. eCollection 2014.

Abstract

Multiple papers have been published regarding the bacterial resistance theme over the last years. A variety of information has reached general and scientific public, daily bringing up data on new resistant microorganisms, new drugs, outbreaks, epidemiological news, resistance gene dissemination, and the lack of information in a particular field has caught our attention: the public health department. Most of researchers, physicians and government employees interpret the public health field as a separate department, not linked to this antibiotic resistance era that we are living nowadays. In this paper we carefully tried to fill in the blanks between public health and the bacteria resistance issue, also considering historical, social, economical and biological problematic that come with this possible pre-antibiotic era.

摘要

在过去几年里,已经发表了多篇关于细菌耐药性主题的论文。各种各样的信息已为普通大众和科学界所知,每天都会带来有关新的耐药微生物、新药、疫情爆发、流行病学新闻、耐药基因传播的数据,而一个特定领域信息的匮乏引起了我们的注意:公共卫生部门。大多数研究人员、医生和政府工作人员将公共卫生领域视为一个独立的部门,与我们如今所处的这个抗生素耐药时代没有关联。在本文中,我们认真尝试填补公共卫生与细菌耐药性问题之间的空白,同时也考虑到这个可能的抗生素前时代所带来的历史、社会、经济和生物学方面的问题。

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本文引用的文献

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The evolution of plasmid-carried antibiotic resistance.质粒携带抗生素耐药性的演变。
BMC Evol Biol. 2011 May 19;11:130. doi: 10.1186/1471-2148-11-130.
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Multidrug-resistant Gram-negative bacteria: how to treat and for how long.耐多药革兰氏阴性菌:如何治疗及治疗时长。
Int J Antimicrob Agents. 2010 Dec;36 Suppl 2:S50-4. doi: 10.1016/j.ijantimicag.2010.11.014. Epub 2010 Dec 3.

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